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一种用于主动协议支持的集成模糊逻辑和基于网络的框架。

An integrated fuzzy logic and web-based framework for active protocol support.

作者信息

Binaghi Elisabetta, Gallo Ignazio, Ghiselli Cristina, Levrini Luca, Biondi Katia

机构信息

Università degli Studi dell'Insubria, Via Ravasi 2, 21100 Varese, Italy.

出版信息

Int J Med Inform. 2008 Apr;77(4):256-71. doi: 10.1016/j.ijmedinf.2007.06.004. Epub 2007 Jul 24.

Abstract

OBJECTIVE

To develop a general purpose web-based system for active support in using protocols.

METHODS

The conceptual model underlying the design of the overall decision support system is drawn from fuzzy set theory and fuzzy logic giving rise to a framework for both acquiring and representing descriptive and operational protocol knowledge. It has been conceived as a web application, designed and implemented according to the technological standards of Internet, in particular XML language and web services, to guarantee distributed functionalities for multicentric studies and the re-use of domain knowledge and problem solving strategies.

RESULTS

Solutions have been evaluated experimentally addressing the specific domain of Temporomandibular disorders (TMD) specializing the general purpose procedures to the dedicated "Research Diagnostic Criteria" (RDC)/TMD protocol. The accuracy of the system was correlated with a set of 50 clinically cases consecutively selected from the Gnatology Department. The results were consistent in 100% of cases. The systematic observation by physicians of both activated rules and diagnostic judgements identified and explicitly formalized additional diagnostic rules in the same context.

CONCLUSIONS

Active protocol support based on fuzzy diagnostic reasoning and advanced web-based technologies shows great potentialities for the renewed role DSSs are called to play in the increasingly wide scale context of evidence-based medicine.

摘要

目的

开发一个基于网络的通用系统,以积极支持协议的使用。

方法

整个决策支持系统设计的概念模型源自模糊集理论和模糊逻辑,从而形成了一个用于获取和表示描述性及操作性协议知识的框架。它被构想为一个网络应用程序,根据互联网技术标准进行设计和实现,特别是XML语言和网络服务,以确保多中心研究的分布式功能以及领域知识和问题解决策略的重用。

结果

针对颞下颌关节紊乱病(TMD)的特定领域对解决方案进行了实验评估,将通用程序专门应用于专用的“研究诊断标准”(RDC)/TMD协议。该系统的准确性与从耳鼻喉科连续选取的50例临床病例相关。结果在100%的病例中是一致的。医生对激活规则和诊断判断的系统观察在相同背景下识别并明确形式化了额外的诊断规则。

结论

基于模糊诊断推理和先进网络技术的主动协议支持显示出决策支持系统在循证医学日益广泛的背景下被要求发挥的新作用具有巨大潜力。

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