Onelöv Erik, Steineck Gunnar, Nyberg Ullakarin, Hauksdóttir Arna, Kreicbergs Ulrika, Henningsohn Lars, Bergmark Karin, Valdimarsdóttir Unnur
Division of Clinical Cancer Epidemiology, Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden.
Acta Oncol. 2007;46(6):810-6. doi: 10.1080/02841860601156124.
We investigated the feasibility of using single-item visual-digital scales for measuring anxiety and depression for research purposes within the oncology and palliative care setting. Data were retrieved from five nationwide postal questionnaires comprising 3030 individuals (response rate 76%): cancer patients, widows/parents who had lost their husband/child to cancer and population controls. All questionnaires contained the Center for Epidemiological Studies Depression scale (CES-D) and Spielberger's State-Trait Anxiety Inventory (STAI-T) as well as seven-point Visual-Digital Scales (VDS) assessing anxiety and depression. Each stepwise increased score on the VDS-depression provided a statistically significant increase in the mean score on CES-D (Spearman's r=0.582). The VDS-anxiety correlated with mean scores on STAI-T (Spearman's r=0.493), however, not all stepwise increased scores on the VDS-anxiety gave a statistically significant increase on the STAI-T. Positive- and negative predictive values were 51% and 91% for VDS-depression and 64% and 80% for VDS-anxiety. Missing data for STAI-T were 7% and 9% for CES-D; the corresponding figures were 2% for the VDS-depression and 3% for VDS-anxiety. With low attrition and agreement with psychometric scales, the Visual-Digital Scales are a feasible alternative for research in the oncology setting. However, the high negative predictive value and the low positive predictive value suggest that the visual- digital scales mainly detect the absence of the symptoms.
我们研究了在肿瘤学和姑息治疗环境中,使用单项视觉数字量表来测量焦虑和抑郁以用于研究目的的可行性。数据来自五份全国性邮政调查问卷,共3030人(回复率76%):癌症患者、因癌症失去丈夫/孩子的寡妇/父母以及普通人群对照。所有问卷都包含流行病学研究中心抑郁量表(CES-D)、斯皮尔伯格状态-特质焦虑量表(STAI-T)以及评估焦虑和抑郁的七点视觉数字量表(VDS)。VDS-抑郁量表上每一步增加的分数,都使CES-D的平均分有统计学上的显著增加(斯皮尔曼相关系数r = 0.582)。VDS-焦虑量表与STAI-T的平均分相关(斯皮尔曼相关系数r = 0.493),然而,VDS-焦虑量表上并非所有逐步增加的分数都能使STAI-T有统计学上的显著增加。VDS-抑郁量表的阳性预测值和阴性预测值分别为51%和91%,VDS-焦虑量表的阳性预测值和阴性预测值分别为64%和80%。STAI-T的缺失数据,CES-D为7%和9%;VDS-抑郁量表和VDS-焦虑量表的相应数字分别为2%和3%。由于损耗率低且与心理测量量表一致,视觉数字量表是肿瘤学研究中一种可行的替代方法。然而,高阴性预测值和低阳性预测值表明,视觉数字量表主要检测症状的不存在。