冠状动脉球囊血管成形术和支架置入术治疗妊娠期急性心肌梗死：替罗非班和氯吡格雷的应用

Treatment of acute myocardial infarction in pregnancy with coronary artery balloon angioplasty and stenting: use of tirofiban and clopidogrel.

作者信息

Boztosun Bilal, Olcay Ayhan, Avci Anil, Kirma Cevat

出版信息

Int J Cardiol. 2008 Jul 21;127(3):413-6. doi: 10.1016/j.ijcard.2007.04.174. Epub 2007 Jul 25.

DOI:10.1016/j.ijcard.2007.04.174

Abstract

Acute myocardial infarction (AMI) in pregnancy is rare and has a high mortality rate of 37-50%. The most important risk factors are advanced maternal age, hypertension and diabetes mellitus. Although thrombolytic therapy, percutaneous transluminal coronary angioplasty (PTCA) and coronary artery by-pass grafting can be performed, primary PTCA and antiplatelet agents have recently improved prognosis. We here present a case of AMI in a 43 year old woman in the 20th week of pregnancy treated successfully with aspirin, clopidogrel and intracoronary stenting without any complications.

摘要

妊娠期急性心肌梗死（AMI）较为罕见，死亡率高达37% - 50%。最重要的危险因素是高龄产妇、高血压和糖尿病。尽管可以进行溶栓治疗、经皮腔内冠状动脉成形术（PTCA）和冠状动脉旁路移植术，但近年来，直接PTCA和抗血小板药物改善了预后。我们在此报告一例43岁女性，在妊娠第20周时发生AMI，成功接受阿司匹林、氯吡格雷和冠状动脉内支架置入治疗，未出现任何并发症。