用天然产品修复骨骼。
Mending the bones with natural products.
作者信息
Sethi Gautam, Aggarwal Bharat B
机构信息
Cytokine Research Laboratory, Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 143, Houston, TX 77030, USA.
出版信息
Chem Biol. 2007 Jul;14(7):738-40. doi: 10.1016/j.chembiol.2007.07.002.
Abstract
In this issue, Qiu and colleagues [1] demonstrate in vitro and in vivo activity of a triterpene glycoside from black cohosh. The isolated compound acts as a suppressor of osteoclastogenesis, targeting specifically RANKL, a member of the TNF superfamily.
摘要
在本期中，邱及其同事[1]展示了黑升麻中一种三萜糖苷的体外和体内活性。分离出的化合物作为破骨细胞生成的抑制剂，特异性靶向肿瘤坏死因子超家族成员RANKL。
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