Jesudanam T Madhuri, Rao G Raghu Rama, Lakshmi D Joga, Kumari G Ratna
Department of Dermatology, King George Hospital & Andhra Medical College, Visakhapatnam, India.
Indian J Dermatol Venereol Leprol. 2002 Nov-Dec;68(6):326-9.
The importance of onychomycosis is often underestimated. Far more than being a simple cosmetic problem, infected nails serve as a chronic reservoir of infection which can give rise to repeated mycotic infections of the skin. 448 patients with nail abnormalities attending Skin O. P. D of King George Hospital, Visakhapatnam during a 1 (one) year period between November'98-October'99, were subjected to detailed clinical, epidemiological study. Diagnosis was confirmed in 204 cases by direct microscopy or culture or by both. Females (51.96%) were slightly more than the males (48.04%). Majority of the cases were between 21-40 years age group. Housewives (33.33%) were most frequently affected. Trauma was a predisposing factor in 11.27% of the cases. The duration of lesions varied from 3 months to 15 years. In the majority (38.23%) it was less than one year. Candidal onychomycosis was the most prevalent clinical type (58.82%) followed by distal subungual onychomycosis (38.72%). Disease was limited only to finger nails in 57.35% and toe nails in 32.35%. Predominant isolates obtained were candida spp. (56.7%), followed by dermatophytes (38.2%) and non-dermatophyte molds (3.37%). 26.96% of the patients had experienced physical, psychosocial and occupational problems.
甲癣的重要性常常被低估。受感染的指甲远不止是一个简单的美容问题,它还是一个慢性感染源,可引发皮肤反复的霉菌感染。在1998年11月至1999年10月的一年期间,对448名前往维沙卡帕特南乔治国王医院皮肤科门诊就诊的指甲异常患者进行了详细的临床和流行病学研究。通过直接显微镜检查、培养或两者结合,在204例中确诊。女性(51.96%)略多于男性(48.04%)。大多数病例在21至40岁年龄组。家庭主妇(33.33%)受影响最为频繁。11.27%的病例中创伤是一个诱发因素。病变持续时间从3个月到15年不等。大多数(38.23%)病例的病变时间不到一年。念珠菌性甲癣是最常见的临床类型(58.82%),其次是远端甲下甲癣(38.72%)。疾病仅局限于手指甲的占57.35%,局限于脚趾甲的占32.35%。分离出的主要菌株是念珠菌属(56.7%),其次是皮肤癣菌(38.2%)和非皮肤癣菌霉菌(3.37%)。26.96%的患者经历过身体、心理社会和职业方面的问题。