Wang Quan Gui
Department of Otorhinolaryngology, Head and Neck Surgery, Peking University First Hospital, Beijing 100034, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2007 Aug 18;39(4):437-9.
Mucosal malignant melanoma of the nasal cavity and paranasal sinuses are rare. Because symptoms and radiological examinations of this disease are generally nonspecific, the diagnosis is often difficult. Diagnosis can be confirmed by the immunohistochemical profile of staining with HMB-45 and S-100. This study deals with two cases of nonspecific clinical features. The factors of misdiagnosis were discussed and the lesson was summarized.
鼻腔和鼻窦黏膜恶性黑色素瘤较为罕见。由于该疾病的症状和影像学检查通常不具有特异性,诊断往往困难。可通过HMB - 45和S - 100染色的免疫组化特征来确诊。本研究涉及两例具有非特异性临床特征的病例。讨论了误诊因素并总结了经验教训。