Korenkov M, Shah S, Sauerland S, Duenschede F, Junginger Th
Department of Surgery, University of Mainz, Germany.
Obes Surg. 2007 May;17(5):679-83. doi: 10.1007/s11695-007-9118-y.
The authors evaluated the impact of laparoscopic adjustable gastric banding (LAGB) on obesity-associated diseases in a series at 3 to 8 years postoperatively, namely diabetes, pulmonary disease, hypertension and knee joint pain.
145 morbidly obese patients underwent LAGB with mean age 38 years and preoperative BMI 48.5 kg/m2 (range 34-77). Changes in BMI and excess BMI loss (EBL) were evaluated.
138 of the 145 patients (95%) were available for full follow-up. At last follow-up, BMI had dropped to 34.0 +/- 6.4 SD kg/m2, and mean EBL was 61.9 +/- 26.1%. Prevalence of obesity-associated disease was significantly reduced: diabetes decreased from 10% to 4%, treatment-requiring pulmonary disease from 15% to 5%, hypertension from 43% to 27%, and knee pain from 47% to 38%.
Following gastric banding, >75% of patients suffering from obesity-related disease had significant decrease or resolution of their co-morbidities.
作者评估了腹腔镜可调节胃束带术(LAGB)对一系列患者术后3至8年肥胖相关疾病的影响,这些疾病包括糖尿病、肺部疾病、高血压和膝关节疼痛。
145例病态肥胖患者接受了LAGB手术,平均年龄38岁,术前体重指数(BMI)为48.5kg/m²(范围34 - 77)。评估了BMI和超重体重减轻(EBL)的变化。
145例患者中有138例(95%)可进行完整随访。在最后一次随访时,BMI降至34.0±6.4标准差kg/m²,平均EBL为61.9±26.1%。肥胖相关疾病的患病率显著降低:糖尿病从10%降至4%,需要治疗的肺部疾病从15%降至5%,高血压从43%降至27%,膝关节疼痛从47%降至38%。
胃束带术后,超过75%患有肥胖相关疾病的患者其合并症显著减轻或得到缓解。