Development, characterization and evaluation of an auto-regulatory delivery system for insulin.
作者信息
Vyas S P, Karajgi J S, Gogoi P J, Jain N K
机构信息
Department of Pharmaceutical Sciences, Dr. H.S. Gour Vishwavidyalaya, Sagar, India.
出版信息
J Microencapsul. 1991 Apr-Jun;8(2):235-42. doi: 10.3109/02652049109071491.
PMID:1765903
Abstract
A self-regulatory delivery system for insulin was designed, based on the competitive and complementary binding behaviour of Concanavalin with glucose and glycosylated insulin. By encapsulating the Con-A bound G- insulin in a suitable polymer membrane, which was permeable to both glucose and insulin, the insulin efflux was regulated in response to glucose influx.
摘要
Zotero 插件