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正电子发射断层扫描(PET)图像重建中用于蒙特卡罗散射系统矩阵的可并行压缩方案。

A parallelizable compression scheme for Monte Carlo scatter system matrices in PET image reconstruction.

作者信息

Rehfeld Niklas, Alber Markus

机构信息

Sektion für Biomedizinische Physik, Klinik für Radioonkologie, Universitätsklinikum Tübingen, Hoppe-Seyler-Str. 3, 72076 Tübingen, Germany.

出版信息

Phys Med Biol. 2007 Jun 21;52(12):3421-37. doi: 10.1088/0031-9155/52/12/007. Epub 2007 May 17.

Abstract

Scatter correction techniques in iterative positron emission tomography (PET) reconstruction increasingly utilize Monte Carlo (MC) simulations which are very well suited to model scatter in the inhomogeneous patient. Due to memory constraints the results of these simulations are not stored in the system matrix, but added or subtracted as a constant term or recalculated in the projector at each iteration. This implies that scatter is not considered in the back-projector. The presented scheme provides a method to store the simulated Monte Carlo scatter in a compressed scatter system matrix. The compression is based on parametrization and B-spline approximation and allows the formation of the scatter matrix based on low statistics simulations. The compression as well as the retrieval of the matrix elements are parallelizable. It is shown that the proposed compression scheme provides sufficient compression so that the storage in memory of a scatter system matrix for a 3D scanner is feasible. Scatter matrices of two different 2D scanner geometries were compressed and used for reconstruction as a proof of concept. Compression ratios of 0.1% could be achieved and scatter induced artifacts in the images were successfully reduced by using the compressed matrices in the reconstruction algorithm.

摘要

迭代正电子发射断层扫描(PET)重建中的散射校正技术越来越多地采用蒙特卡罗(MC)模拟,这种模拟非常适合对非均匀患者体内的散射进行建模。由于内存限制,这些模拟的结果不会存储在系统矩阵中,而是作为常数项相加或相减,或者在每次迭代时在投影仪中重新计算。这意味着在反投影仪中不考虑散射。本文提出的方案提供了一种将模拟的蒙特卡罗散射存储在压缩散射系统矩阵中的方法。压缩基于参数化和B样条近似,并允许基于低统计模拟形成散射矩阵。矩阵元素的压缩和检索都是可并行化的。结果表明,所提出的压缩方案提供了足够的压缩,使得在内存中存储三维扫描仪的散射系统矩阵是可行的。对两种不同二维扫描仪几何形状的散射矩阵进行了压缩,并将其用于重建以验证概念。可以实现0.1%的压缩率,并且通过在重建算法中使用压缩矩阵成功减少了图像中的散射诱导伪影。

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