Abascal Juan-Felipe P J, Arridge Simon R, Lionheart William R B, Bayford Richard H, Holder David S
Department of Medical Physics, University College London, London, UK.
Physiol Meas. 2007 Jul;28(7):S129-40. doi: 10.1088/0967-3334/28/7/S10. Epub 2007 Jun 26.
Electrical impedance tomography is an imaging method, with which volumetric images of conductivity are produced by injecting electrical current and measuring boundary voltages. It has the potential to become a portable non-invasive medical imaging technique. Until now, implementations have neglected anisotropy even though human tissues such as bone, muscle and brain white matter are markedly anisotropic. We present a numerical solution using the finite-element method that has been modified for modelling anisotropic conductive media. It was validated in an anisotropic domain against an analytical solution in an isotropic medium after the isotropic domain was diffeomorphically transformed into an anisotropic one. Convergence of the finite element to the analytical solution was verified by showing that the finite-element error norm decreased linearly related to the finite-element size, as the mesh density increased, for the simplified case of Laplace's equation in a cubic domain with a Dirichlet boundary condition.
电阻抗断层成像术是一种成像方法,通过注入电流并测量边界电压来生成电导率的体积图像。它有潜力成为一种便携式非侵入性医学成像技术。到目前为止,尽管诸如骨骼、肌肉和脑白质等人体组织具有明显的各向异性,但相关实现一直忽略了各向异性。我们提出了一种使用有限元方法的数值解,该方法已针对各向异性导电介质建模进行了修改。在将各向同性域微分同胚变换为各向异性域后,在各向异性域中针对各向同性介质中的解析解对其进行了验证。对于具有狄利克雷边界条件的立方域中拉普拉斯方程的简化情况,通过表明随着网格密度增加,有限元误差范数与有限元大小呈线性下降,验证了有限元向解析解的收敛性。