[A method for calculating the additional quantity of protamine sulfate during cardiosurgical operations].

The paper describes a method for calculating the additional dose of protamine sulfate solution during incomplete heparin neutralization after cardiac surgery under extracorporeal circulation, by estimating the anti-Xa-activity of venous blood plasma. The method may be an alternative to the use of devices to measure the blood concentration of free heparin, such as a "Hepcon" apparatus.