一种用于合成苯并呋喃醌衍生物的环保电化学方法。

An environmentally friendly electrochemical method for synthesis of benzofuranoquinone derivatives.

作者信息

Davarani Saied Saeed Hosseiny, Shamsipur Mojtaba, Nematollahi Davood, Ramyar Somayyeh, Masoumi Leila

机构信息

Department of Chemistry, Faculty of Science, Shahid Beheshti University, Tehran, Iran.

出版信息

Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1198-202. doi: 10.1248/cpb.55.1198.

DOI:10.1248/cpb.55.1198

PMID:17666844

Abstract

Electrochemical oxidation of catechols (1a-c) has been studied in the presence of 2-hydroxy-1,4-naphtoquinone (3b) in aqueous solutions, using cyclic voltammetry and controlled-potential coulometry. The results indicated that the electrochemically generated o-benzoquinones (2a-c) participate in Michael addition reaction with 3b to the corresponding benzofuranoquinones (8a-c, 10a-c). The electrochemical synthesis of these compounds has been successfully preformed at a carbon rod electrode with good yields using an environmentally friendly method.

摘要

在水溶液中，利用循环伏安法和控制电位库仑法，研究了邻苯二酚（1a - c）在2 - 羟基 - 1,4 - 萘醌（3b）存在下的电化学氧化。结果表明，电化学生成的邻苯醌（2a - c）与3b发生迈克尔加成反应生成相应的苯并呋喃醌（8a - c，10a - c）。使用环保方法，已在碳棒电极上成功地电化学合成了这些化合物，产率良好。