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α干扰素制剂在儿童急性淋巴细胞白血病缓解期的应用

[Use of alpha interferon preparations in acute lymphoblastic leukemia in children during remission].

作者信息

Gavrilova I E, Kuznetsov I P, Denisov L A, Maiakova S A, Orlova T G, Kadagidze Z G, Makhonova L A

出版信息

Pediatriia. 1991(11):75-8.

PMID:1766748
Abstract

The Soviet alpha-interferon drugs (human leukocytic interferon, reaferon) were used in the program of the treatment of children with acute lymphoblastic leukemia (during remission). The treatment was found to be more effective with an increase of its duration, relapse-free course of the disease (69.4-82.3%) and survival (70.1-93.1%) of patients with an unfavourable disease prognosis (over 5 years).

摘要

苏联的α-干扰素药物(人白细胞干扰素,瑞芬)被用于治疗急性淋巴细胞白血病儿童(缓解期)的方案中。结果发现,对于疾病预后不良的患者(超过5年),随着治疗时间的延长,治疗效果更佳,疾病无复发生存率(69.4 - 82.3%)和生存率(70.1 - 93.1%)均有所提高。

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