Mierzwiński Józef, Krzyzaniak Andrzej, Fishman Andrew J, Dalke Krzysztof, Burduk Paweł, Wegrzynowska Ewa
Katedra i Klinika Otolaryngologii, Collegium Medicum im. Rydygiera w Bydgoszczy, Uniwersytetu Mikołaja Kopernika w Toruniu.
Otolaryngol Pol. 2007;61(2):147-51. doi: 10.1016/s0030-6657(07)70403-1.
Diagnosis and management of perilymphatic fistula (PLF) is a controversial topic in the international neurotologic literature. An illustrative case of post traumatic PLF with clear surgical indications is presented. This manuscript also reviews the various clinical presentations, pathogenesis, diagnostic examinations, and management options of PLF.
Case report and literature review.
A 40 y/o female presented with paroxysmal vertigo, imbalance and severe sensorineural hearing loss (SNHL) following minor occipital head trauma from a fall six months prior to presentation. Laboratory examination included intermittently positive fistula sign on video-nystagmography. Patient failed to respond to trials of pharmacologic treatment and bedrest and ultimately underwent surgical exploration and repair. Patient had earlobe fat placed in the round and oval windows. Postoperatively, she had prompt resolution of vestibulopathy and ultimate full return of sensorineural function.
Patients with appropriate antecedent history demonstrating fluctuating SNHL and vestibulopathy, failing to respond to conservative medical treatments, should be considered for exploratory tympanotomy. In the absence of any other violations of labyrinthine integrity, connective tissue grafting of the round and oval windows should be performed even if no obvious flow of fluid is observed. This management protocol is safe and effective in properly selected patients.
外淋巴瘘(PLF)的诊断与治疗是国际神经耳科学文献中一个颇具争议的话题。本文介绍了一例有明确手术指征的创伤后PLF病例。本文还综述了PLF的各种临床表现、发病机制、诊断检查及治疗选择。
病例报告及文献综述。
一名40岁女性在就诊前六个月因摔倒导致枕部轻微头部外伤后,出现阵发性眩晕、平衡失调及严重感音神经性听力损失(SNHL)。实验室检查包括视频眼震图检查时瘘管征间歇性阳性。患者对药物治疗及卧床休息试验无反应,最终接受了手术探查及修复。术中在圆窗和卵圆窗植入耳垂脂肪。术后,她的前庭病变迅速缓解,感音神经功能最终完全恢复。
有适当既往史、表现为波动性SNHL和前庭病变且对保守药物治疗无反应的患者,应考虑进行探查性鼓室切开术。在没有其他迷路完整性破坏的情况下,即使未观察到明显的液体流动,也应进行圆窗和卵圆窗的结缔组织移植。这种治疗方案在适当选择的患者中是安全有效的。