Feldkamp J M, Schroer C G, Patommel J, Lengeler B, Günzler T F, Schweitzer M, Stenzel C, Dieckmann M, Schroeder W H
Institut für Strukturphysik, University of Technology Dresden, D-01062 Dresden, Germany.
Rev Sci Instrum. 2007 Jul;78(7):073702. doi: 10.1063/1.2751094.
We have designed and built a compact x-ray microtomography system to perform element mapping and absorption imaging by exploiting scanning fluorescence tomography and full-field transmission microtomography, respectively. It is based on a low power microfocus tube and is potentially appropriate for x-ray diagnostics in space. Full-field transmission tomography yields the three-dimensional inner structure of an object. Fluorescence microtomography provides the element distribution on a virtual section through the sample. Both techniques can be combined for appropriate samples. Microradiography as well as fluorescence mapping are also possible. For fluorescence microtomography a small and intensive microbeam is required. It is generated using a polycapillary optic. Operating the microfocus tube with a molybdenum target at 12 W, a microbeam with a full width at half maximum lateral extension of 16 microm and a flux of about 10(8) photonss is generated. As an example of application, this beam is used to determine the element distribution inside dried plant samples. For full-field scanning tomography, the x-ray optic is removed and the sample is imaged in magnifying projection onto a two-dimensional position sensitive detector. Depending on the sample size, a spatial resolution down to about 10 microm is possible in this mode. The method is demonstrated by three-dimensional imaging of a rat humerus.
我们设计并构建了一种紧凑型X射线显微断层扫描系统,分别利用扫描荧光断层扫描和全场透射显微断层扫描来进行元素映射和吸收成像。该系统基于低功率微焦点管,可能适用于空间X射线诊断。全场透射断层扫描可得出物体的三维内部结构。荧光显微断层扫描可提供穿过样品的虚拟截面的元素分布。这两种技术可针对合适的样品进行组合。微放射成像以及荧光映射也是可行的。对于荧光显微断层扫描,需要一个小而强的微束。它是使用聚束毛细管光学器件产生的。以12瓦的功率运行带有钼靶的微焦点管时,可产生半高宽横向扩展为16微米且通量约为10⁸光子的微束。作为应用示例,该微束用于确定干燥植物样品内部的元素分布。对于全场扫描断层扫描,移除X射线光学器件,将样品以放大投影的方式成像到二维位置敏感探测器上。根据样品大小,在此模式下可实现低至约10微米的空间分辨率。通过对大鼠肱骨进行三维成像展示了该方法。