Pamir M Necmettin, Peker Selçuk, Bayrakli Fatih, Kiliç Türker, Ozek M Memet
Department of Neurosurgery, Marmara University, Neurological Sciences Institute, Acibadem Kozyatagi Hospital, Istanbul, Turkey.
Neurosurg Rev. 2007 Oct;30(4):329-37; discussion 337. doi: 10.1007/s10143-007-0093-5. Epub 2007 Aug 4.
Schwannomas that arise from the trigeminal nerve are rare, but this nerve is the second most frequent intracranial site of schwannoma occurrence next to the vestibular nerve. The advent of microsurgical techniques and skull-base approaches has greatly enhanced the surgical management of these tumors, and outcomes have improved markedly. This report documents 18 cases of histologically verified schwannomas that arose from the trigeminal nerve and were treated surgically in our clinic between January 1992 and July 2005. The patients were ten women and eight men of age 39.7 years (range, 22-62 years). The tumor was located in the middle fossa (type A) in five cases, in the middle and posterior fossae (type C) in nine cases, in the posterior fossa (type B) in two cases, and in the branches of the trigeminal nerve (type D) in two cases. Total excision was achieved in 17 cases, and there was no mortality in the series. Our results indicate that trigeminal schwannomas, regardless of type, can be removed via skull-base approaches. We present an algorithm for surgical management of trigeminal schwannomas based on our experience and information from the literature.
起源于三叉神经的神经鞘瘤较为罕见,但该神经是仅次于前庭神经的第二常见的颅内神经鞘瘤发生部位。显微外科技术和颅底入路的出现极大地改善了这些肿瘤的手术治疗,治疗效果也有了显著提高。本报告记录了1992年1月至2005年7月间在我院接受手术治疗的18例经组织学证实的起源于三叉神经的神经鞘瘤。患者中女性10例,男性8例,年龄39.7岁(范围22 - 62岁)。肿瘤位于中颅窝(A型)5例,中后颅窝(C型)9例,后颅窝(B型)2例,三叉神经分支(D型)2例。17例实现了全切,该系列无死亡病例。我们的结果表明,无论何种类型的三叉神经鞘瘤,均可通过颅底入路切除。我们根据自身经验和文献资料提出了一种三叉神经鞘瘤的手术治疗方案。