Bueno J
Unidadde Trasplante Hepático Pediáitrico, Departamento de Cirugía Pediátrica, Hospital Vall d'Hebrón, Barcelona, España.
Nutr Hosp. 2007 May;22 Suppl 2:103-12.
Management of short bowel syndrome has to be undertaken by a multidisciplinary team including gastroenterology, surgery, and nutrition, among other specialties. The final therapeutic goal is favoring intestinal adaptation by the bowel so that the patient may be weaned from parenteral nutrition. Anatomical factors influencing on adaptation are very important for deciding the best surgical option. The type of procedure will defined by age, length and functionality of the remnant bowel, the existence of intestinal dilation, the presence of bacterial overgrowth, and the presence or absence of parenteral nutrition-related complications, among others. Early closure of the stomas, if present, and correction of stenoses, if possible with stricturoplasties and with remodeling or intestinal plicature if needed, are among the basic principles of surgical management. Interventions aimed at decreasing the transit time such as the creation of valves, interposition of anti-peristaltic segments or large bowel are poorly accepted. The most accepted techniques are those elongating the bowel that may be applied only on dilated bowels. Although experience is greater with Bianchi's technique, short-term outcomes of serial transversal enteroplasty (STEP) are promising. STEP is simpler and may be applied even to previously elongated bowels by the Bianchi's technique.
短肠综合征的管理必须由包括胃肠病学、外科和营养等多个专业的多学科团队来进行。最终的治疗目标是促进肠道的适应性,以便患者能够停用肠外营养。影响适应性的解剖学因素对于决定最佳手术方案非常重要。手术方式将由残余肠管的年龄、长度和功能、肠道扩张的存在、细菌过度生长的存在以及肠外营养相关并发症的有无等因素决定。如果存在造口,尽早关闭造口;如果可能,纠正狭窄,必要时采用狭窄成形术以及重塑或肠折叠术,这些都是手术管理的基本原则。旨在缩短转运时间的干预措施,如创建瓣膜、插入抗蠕动段或大肠,不太被接受。最被接受的技术是那些延长肠道的技术,这些技术仅适用于扩张的肠道。虽然 Bianchi 技术的经验更丰富,但连续横向肠成形术(STEP)的短期效果很有前景。STEP 更简单,甚至可以应用于之前通过 Bianchi 技术延长过的肠道。