Levy Adrian R, Sobolev Boris G, Kuramoto Lisa, Hayden Robert, MacLeod Stuart M
Department of Health Care and Epidemiology, University of British Columbia (BC), Vancouver, Canada.
BMC Cardiovasc Disord. 2007 Aug 2;7:24. doi: 10.1186/1471-2261-7-24.
Studies have shown patients who are delayed for surgical cardiac revascularization are faced with increased risks of symptom deterioration and death. This could explain the observation that operative mortality among persons undergoing coronary artery bypass surgery (CABG) is higher among women than men. However, in jurisdictions that employ priority wait lists to manage access to elective cardiac surgery, there is little information on whether women wait longer than men for CABG. It is therefore difficult to ascertain whether higher operative mortality among women is due to biological differences or to delayed access to elective CABG.
Using records from a population-based registry, we compared the wait-list time between women and men in British Columbia (BC) between 1990 and 2000. We compared the number of weeks from registration to surgery for equal proportions of women and men, after adjusting for priority, comorbidity and age.
In BC in the 1990 s, 9,167 patients aged 40 years and over were registered on wait lists for CABG and spent a total of 136,071 person-weeks waiting. At the time of registration for CABG, women were more likely to have a comorbid condition than men. We found little evidence to suggest that women waited longer than men for CABG after registration, after adjusting for comorbidity and age, either overall or within three priority groups.
Our findings support the hypothesis that higher operative mortality during elective CABG operations observed among women is not due to longer delays for the procedure.
研究表明,接受心脏外科血管重建手术延迟的患者面临症状恶化和死亡风险增加的情况。这可以解释为何接受冠状动脉搭桥手术(CABG)的女性患者手术死亡率高于男性。然而,在采用优先等待名单来管理择期心脏手术准入的地区,关于女性等待冠状动脉搭桥手术的时间是否比男性更长的信息很少。因此,很难确定女性较高的手术死亡率是由于生物学差异还是择期冠状动脉搭桥手术的延迟准入。
利用基于人群的登记处记录,我们比较了1990年至2000年期间不列颠哥伦比亚省(BC)女性和男性的等待名单时间。在调整了优先级、合并症和年龄后,我们比较了同等比例的女性和男性从登记到手术的周数。
在20世纪90年代的BC省,9167名40岁及以上的患者被登记在冠状动脉搭桥手术的等待名单上,总共花费了136071人周的等待时间。在登记冠状动脉搭桥手术时,女性比男性更有可能患有合并症。在调整合并症和年龄后,无论是总体还是在三个优先级组内,我们几乎没有发现证据表明女性在登记后等待冠状动脉搭桥手术的时间比男性更长。
我们的研究结果支持这样的假设,即女性在择期冠状动脉搭桥手术中观察到的较高手术死亡率并非由于手术延迟时间更长。