Suppr
超能文献

RNA polymerase: the most specific damage recognition protein in cellular responses to DNA damage?

作者信息

Lindsey-Boltz Laura A, Sancar Aziz

机构信息

Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, NC 27599-7260, USA.

出版信息

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13213-4. doi: 10.1073/pnas.0706316104. Epub 2007 Aug 7.

DOI:10.1073/pnas.0706316104

PMID:17684092

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1948916/

Abstract

摘要

相似文献

RNA polymerase: the most specific damage recognition protein in cellular responses to DNA damage?

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13213-4. doi: 10.1073/pnas.0706316104. Epub 2007 Aug 7.

DNA photodamage recognition by RNA polymerase II.

FEBS Lett. 2007 Jun 19;581(15):2757-60. doi: 10.1016/j.febslet.2007.05.014. Epub 2007 May 11.

Damage control: DNA repair, transcription, and the ubiquitin-proteasome system.

DNA Repair (Amst). 2009 Apr 5;8(4):444-8. doi: 10.1016/j.dnarep.2009.01.017. Epub 2009 Mar 9.

Blockage of RNA polymerase II at a cyclobutane pyrimidine dimer and 6-4 photoproduct.

Biochem Biophys Res Commun. 2004 Aug 6;320(4):1133-8. doi: 10.1016/j.bbrc.2004.06.066.

Shedding UV light on alternative splicing.

Cell. 2009 May 15;137(4):600-2. doi: 10.1016/j.cell.2009.04.054.

CPD damage recognition by transcribing RNA polymerase II.

Science. 2007 Feb 9;315(5813):859-62. doi: 10.1126/science.1135400.

DNA polymerase epsilon associates with the elongating form of RNA polymerase II and nascent transcripts.

FEBS J. 2006 Dec;273(24):5535-49. doi: 10.1111/j.1742-4658.2006.05544.x.

A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage.

Nature. 2002 Feb 21;415(6874):929-33. doi: 10.1038/415929a.

Assays for transcription elongation by RNA polymerase II using oligo(dC)-tailed template with single DNA damage.

Methods Enzymol. 2006;408:214-23. doi: 10.1016/S0076-6879(06)08013-X.

A cellular defense pathway regulating transcription through poly(ADP-ribosyl)ation in response to DNA damage.

Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):9886-91. doi: 10.1073/pnas.170280397.

引用本文的文献

Molecular model of TFIIH recruitment to the transcription-coupled repair machinery.

Nat Commun. 2025 Mar 8;16(1):2341. doi: 10.1038/s41467-025-57593-0.

The ARK2N-CK2 complex initiates transcription-coupled repair through enhancing the interaction of CSB with lesion-stalled RNAPII.

Proc Natl Acad Sci U S A. 2024 Jun 11;121(24):e2404383121. doi: 10.1073/pnas.2404383121. Epub 2024 Jun 6.

Conventional DNA-Damaging Cancer Therapies and Emerging cGAS-STING Activation: A Review and Perspectives Regarding Immunotherapeutic Potential.

Cancers (Basel). 2023 Aug 16;15(16):4127. doi: 10.3390/cancers15164127.

Dynamic conformational switching underlies TFIIH function in transcription and DNA repair and impacts genetic diseases.

Nat Commun. 2023 May 13;14(1):2758. doi: 10.1038/s41467-023-38416-6.

A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV.

Nucleic Acids Res. 2022 Aug 26;50(15):e89. doi: 10.1093/nar/gkac434.

Mechanism of Rad26-assisted rescue of stalled RNA polymerase II in transcription-coupled repair.

Nat Commun. 2021 Dec 1;12(1):7001. doi: 10.1038/s41467-021-27295-4.

Mfd - at the crossroads of bacterial DNA repair, transcriptional regulation and molecular evolvability.

Transcription. 2021 Aug;12(4):156-170. doi: 10.1080/21541264.2021.1982628. Epub 2021 Oct 21.

A Nobel-Winning Scientist: Aziz Sancar and the Impact of his Work on the Molecular Pathology of Neoplastic Diseases.

Turk Patoloji Derg. 2021;37(2):93-105. doi: 10.5146/tjpath.2020.01504.

The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites.

Int J Mol Sci. 2021 Mar 25;22(7):3379. doi: 10.3390/ijms22073379.

A Peek Inside the Machines of Bacterial Nucleotide Excision Repair.

Int J Mol Sci. 2021 Jan 19;22(2):952. doi: 10.3390/ijms22020952.

本文引用的文献

Reconstitution of a human ATR-mediated checkpoint response to damaged DNA.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13301-6. doi: 10.1073/pnas.0706013104. Epub 2007 Aug 8.

RPA and ATR link transcriptional stress to p53.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12778-83. doi: 10.1073/pnas.0705317104. Epub 2007 Jul 6.

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.

Nature. 2007 Jun 14;447(7146):799-816. doi: 10.1038/nature05874.

Single- and double-stranded DNA: building a trigger of ATR-mediated DNA damage response.

Genes Dev. 2007 Apr 15;21(8):879-85. doi: 10.1101/gad.1550307.

Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cells.

J Cell Sci. 2007 Mar 15;120(Pt 6):1104-12. doi: 10.1242/jcs.03391. Epub 2007 Feb 27.

DNA nucleotide excision repair-dependent signaling to checkpoint activation.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17325-30. doi: 10.1073/pnas.0605446103. Epub 2006 Nov 6.

H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks.

Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9891-6. doi: 10.1073/pnas.0603779103. Epub 2006 Jun 20.

Recruitment of DNA damage checkpoint proteins to damage in transcribed and nontranscribed sequences.

Mol Cell Biol. 2006 Jan;26(1):39-49. doi: 10.1128/MCB.26.1.39-49.2006.

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation.

Nature. 2005 Nov 24;438(7067):508-11. doi: 10.1038/nature04255. Epub 2005 Oct 26.

Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function.

Annu Rev Biochem. 2005;74:317-53. doi: 10.1146/annurev.biochem.74.082803.133250.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Suppr超能文献

RNA polymerase: the most specific damage recognition protein in cellular responses to DNA damage?

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译