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氟-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描用于阴茎癌患者以制定合适的治疗策略。

Fluoro-18 fluorodeoxyglucose positron emission tomography/computerized tomography scans in a patient with penile cancer for appropriate therapeutic strategy.

作者信息

Halac Metin, Zincirkeser Sabri, Sönmezoglu Kerim, Sager Sait, Durak Haydar, Uslu Ilhami

机构信息

Department of Nuclear Medicine, Cerrahpasa Medicine School of Istanbul University Aksaray/Istanbul, Turkey.

出版信息

Hell J Nucl Med. 2007 May-Aug;10(2):113-5.

Abstract

In patients with penile cancer, positron emission tomography (PET) is important for identifying metastatic lesions and for therapeutic strategy planning. By using PET/computerised tomography -CT scanning, more precise localization and attenuation correction is provided by CT as an additional advantage for diagnosis. A 78-year-old man with squamous cell cancer of the glans penis diagnosed after histopathological examination was referred to our Nuclear Medicine Department PET/CT unit by the Urology Department of our Hospital, for investigation of metastases and for therapeutic strategy planning. There was significantly increased focal fluoro-18 fluorodeoxyglucose (18F-FDG) activity (SUV: 18.2) in the glans penile area and slightly increased activity in the right inguinal region which was described as inflammation by the histopathological examination. There was no other increased abnormal 18F-FDG activity. 18F-FDG PET or PET/CT may be used in squamous cell cancer of the penis for the detection of metastases and for therapeutic strategy planning. Finally, invasive procedures such as total bilateral inguinal lymphadenectomy, having a high morbidity, may be avoided.

摘要

对于阴茎癌患者,正电子发射断层扫描(PET)对于识别转移病灶和制定治疗策略至关重要。通过使用PET/计算机断层扫描(CT),CT可提供更精确的定位和衰减校正,这是诊断的另一个优势。一名78岁男性,经组织病理学检查诊断为阴茎头鳞状细胞癌,由我院泌尿外科转诊至核医学科PET/CT室,以评估转移情况并制定治疗策略。阴茎头区域氟代脱氧葡萄糖(18F-FDG)局部活性显著增加(SUV:18.2),右侧腹股沟区活性略有增加,组织病理学检查认为是炎症。未发现其他18F-FDG活性异常增加。18F-FDG PET或PET/CT可用于阴茎鳞状细胞癌转移灶的检测和治疗策略的制定。最后,可避免进行双侧腹股沟淋巴结清扫术等具有较高发病率的侵入性手术。

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