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[胸腰椎创伤性固定性后凸畸形脊柱截骨术的解剖学与临床研究]

[Anatomic and clinical study of spinal osteotomies for traumatic fixed kyphotic deformity of thoracolumbar spine].

作者信息

Sun Tian-sheng, Li Fang, Liu Zhi, Liu Shu-qing, Zhang Zhi-cheng

机构信息

Department of Orthopaedics, Beijing Army General Hospital, Beijing 100700, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2007 Apr 15;45(8):533-6.

Abstract

OBJECTIVE

To investigate the safety and efficiency of spinal osteotomies for traumatic fixed kyphotic deformity of thoracolumbar spine with spinal cord injury.

METHODS

Single-level vertebral osteotomies were performed on 3 groups of fresh-frozen human cadaveric lumbar spines. Group 1 underwent a conventional anterior opening-wedge or posterior closing-wedge osteotomy, Group 2 underwent a conventional decancellation posterior closing-wedge osteotomy, and Group 3 underwent the modified decancellation posterior closing-wedge osteotomy. Sagittal plane angulation as well as anterior height and distance of the spinal column were measured before and after osteotomy. In the clinical study, 26 cases of old thoracolumbar fractures with spinal cord injury, 36 years in average, were recruited in this study. The mean time from injury to this operation was 25 months ranging from 3 months to 11 years. Prior to the index surgery, 9 patients received conservative treatment, and 17 patients underwent surgical treatment. There were complete paraplegia in 10 cases and incomplete paraplegia in 14 cases (Frankel B 2 cases, C 10 and D 2). The patients suffered from the low back pain, the average score of VAS was 4.5 (2.5 - 6.0). The patients were found with remained kyphotic deformity of a mean 35 degrees (20 degrees - 75 degrees ). According to the deformity angles, conventional or modified decancellation posterior closing-wedge osteotomy was performed.

RESULTS

On 3 groups of fresh-frozen human cadaveric lumbar spines, the mean correction was (38.0 +/- 2.5) degrees for Group 1, (36.0 +/- 3.6) degrees for Group 2, and (49.0 +/- 2.0) degrees for Group 3. The mean change in anterior height and distance was (13.8 +/- 1.4) mm and (30.2 +/- 2.5) mm respectively for Group 1. For Groups 2 and 3 it was only 2 - 4 mm. In clinical trial, all cases were followed up for 10 months to 6 years, average 12.5 months. Successful decompression and satisfied correction of kyphosis was noticed. The post-operatively mean angle of kyphosis deformity was 10.8 degrees , ranging from 0 degrees to 40 degrees . Neurological functional recovery was noticed in 50% of all cases. For complete spinal cord injury, 30% of cases partially recovered (sensory function), whereas neurological function recovery was noted in 64.3% of cases with incomplete spinal cord injury, a statistical difference was showed between the incomplete and complete spinal cord injury cases (P < 0.01). The score of VAS was 2.3 (1.0 - 3.5) at last follow-up.

CONCLUSIONS

The traumatic fixed kyphotic deformity of thoracolumbar spine with spinal cord injury could be treated with conventional or modified decancellation posterior closing-wedge osteotomy, neurological function and low back pain were expectably recovered.

摘要

目的

探讨脊柱截骨术治疗胸腰段脊柱创伤性固定性后凸畸形伴脊髓损伤的安全性和有效性。

方法

对3组新鲜冷冻的人尸体腰椎进行单节段椎体截骨术。第1组行传统的前路开口楔形或后路闭合楔形截骨术,第2组行传统的去皮质后路闭合楔形截骨术,第3组行改良的去皮质后路闭合楔形截骨术。在截骨术前和术后测量矢状面成角以及脊柱的前高度和距离。在临床研究中,招募了26例平均年龄36岁的陈旧性胸腰段骨折伴脊髓损伤患者。受伤至此次手术的平均时间为25个月,范围为3个月至11年。在初次手术前,9例患者接受了保守治疗,17例患者接受了手术治疗。其中完全性截瘫10例,不完全性截瘫14例(Frankel B级2例、C级10例、D级2例)。患者均有腰痛,VAS平均评分为4.5(2.5 - 6.0)。患者均存在残留后凸畸形,平均为35度(20度 - 75度)。根据畸形角度,行传统或改良的去皮质后路闭合楔形截骨术。

结果

在3组新鲜冷冻的人尸体腰椎上,第1组平均矫正角度为(38.0±2.5)度,第2组为(36.0±3.6)度,第3组为(49.0±2.0)度。第1组前高度和距离的平均变化分别为(13.8±1.4)mm和(30.2±2.5)mm。第2组和第3组仅为2 - 4 mm。在临床试验中,所有病例均随访10个月至6年,平均12.5个月。观察到成功减压和后凸畸形得到满意矫正。术后后凸畸形的平均角度为10.8度,范围为0度至40度。所有病例中有50%观察到神经功能恢复。对于完全性脊髓损伤,30%的病例部分恢复(感觉功能),而不完全性脊髓损伤病例中有64.3%观察到神经功能恢复,不完全性和完全性脊髓损伤病例之间存在统计学差异(P < 0.01)。末次随访时VAS评分为2.3(1.0 - 3.5)。

结论

胸腰段脊柱创伤性固定性后凸畸形伴脊髓损伤可采用传统或改良的去皮质后路闭合楔形截骨术治疗,有望恢复神经功能和缓解腰痛。

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