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[腹部结核——外科实际情况]

[Abdominal tuberculosis--a surgical reality].

作者信息

Târcoveanu E, Filip V, Moldovanu R, Dimofte G, Lupaşcu C, Vlad N, Vasilescu A, Epure Oana

机构信息

Clinica I Chirurgie, Spitalul Sf. Spiridon, Iaşi.

出版信息

Chirurgia (Bucur). 2007 May-Jun;102(3):303-8.

Abstract

Abdominal tuberculosis is a rare disease, with non-specific findings. Peritoneal tuberculosis is a frequent cause of low gradient ascites. The records of 22 patients (Il males, 11 females, mean age 41,17 years, and range 17-74 years) diagnosed with abdominal tuberculosis (TBC) in First Surgical Clinic, "St. Spiridon" University Hospital Iaşi between 1995 and 2006 were analyzed retrospectively and the literature was reviewed. From these 22 patients diagnosed with abdominal tuberculosis, there were: peritoneal TBC in 16 cases, intestinal TBC in 5 cases, mesenteric lymph nodes TBC in 1 case. The patients with intestinal TBC, were presented with complications, 2 perforations with peritonitis, 1 intestinal obstruction, and 2 as ileo-cecal "tumors" solved by right colectomy, 4 enterectomy (3 entero-enterostomies and 1 ileo-colic anastomosis). The patients with peritoneal TBC were diagnosed by laparoscopy and peritoneal biopsy in 13 cases, and by laparotomy in 3 cases. In peritoneal tuberculosis ascites was present in 15 cases. Other common findings were weight loss (12 cases), weakness (5 cases), abdominal pain (15 cases), anorexia (5 cases) and night sweat (2 cases). Only two patients had chest radiography suggestive of a new TBC lesion. In those patients with peritoneal tuberculosis, subjected to operation, the findings were multiple diffuse involvements of the visceral and parietal peritoneum, white "miliary nodules" or plaques, enlarged lymph nodes, ascites, "violin string" fibrinous strands, and omental thickening. Biopsy specimens showed granulomas, while ascitic fluid showed numerous lymphocytes. Post operatory evolution and management were applied by the TBC Medical System and the patients were treated 6 months by tuberculostatics, with favorable evolution. Abdominal tuberculosis should be considered for diagnosis, in patients with non-specific symptoms of abdominal pain, fever, loss of appetite, abdominal distension and even symptoms of acute abdomen. Laparoscopy is the best approach for peritoneal tuberculosis, and emergency surgery is necessary for acute complication like obstruction and peritonitis. Specific antituberculosis drugs are indicated in postoperative period.

摘要

腹部结核是一种罕见疾病,表现不具特异性。结核性腹膜炎是低梯度腹水的常见病因。对1995年至2006年间在雅西“圣斯皮里东”大学医院第一外科诊所确诊为腹部结核(TBC)的22例患者(11例男性,11例女性,平均年龄41.17岁,年龄范围17 - 74岁)的病历进行回顾性分析并复习相关文献。在这22例确诊为腹部结核的患者中,有:16例为结核性腹膜炎,5例为肠结核,1例为肠系膜淋巴结结核。肠结核患者出现了并发症,2例穿孔伴腹膜炎,1例肠梗阻,2例表现为回盲部“肿瘤”,经右半结肠切除术治愈,4例行肠切除术(3例肠 - 肠吻合术和1例回肠 - 结肠吻合术)。结核性腹膜炎患者中,13例通过腹腔镜检查及腹膜活检确诊,3例通过剖腹手术确诊。15例结核性腹膜炎患者存在腹水。其他常见表现包括体重减轻(12例)、乏力(5例)、腹痛(15例)、厌食(5例)和盗汗(2例)。仅2例患者胸部X线检查提示有新的结核病灶。对于接受手术的结核性腹膜炎患者,术中所见为脏层和壁层腹膜的多发性弥漫性受累、白色“粟粒结节”或斑块、肿大的淋巴结、腹水、“小提琴弦”样纤维条索以及网膜增厚。活检标本显示肉芽肿,腹水显示大量淋巴细胞。术后按照结核病医疗体系进行病情演变观察及处理,患者接受了6个月的抗结核药物治疗,病情转归良好。对于有腹痛、发热、食欲不振、腹胀等非特异性症状甚至急腹症症状的患者,应考虑诊断腹部结核。腹腔镜检查是诊断结核性腹膜炎的最佳方法,对于肠梗阻和腹膜炎等急性并发症则需要急诊手术。术后需使用特异性抗结核药物。

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