Chee Michael W L, Tan Jiat Chow
Cognitive Neuroscience Laboratory, Duke-NUS Graduate Medical School and SingHealth, No. 7 Hospital Drive Blk. B #01-11 Singapore 169611, Singapore.
Neuroimage. 2007 Oct 1;37(4):1487-95. doi: 10.1016/j.neuroimage.2007.07.006. Epub 2007 Jul 18.
fMR adaptation in the ventral visual pathway reflects information processing that may contribute to implicit and explicit memory. In experiments that employed <1 s repetition lag, we found that attention increases adaptation for repeated objects in brain regions at the top of the visual processing hierarchy (anterior fusiform and parahippocampal gyri) but that it can still appear with minimal attention in most of the fusiform bilaterally. Of the ventral visual regions showing adaptation, the parahippocampal region and LOC showed the strongest correlation between adaptation magnitude and recognition memory across subjects. Although there was some overlap, regions showing correlations between adaptation and priming lay more posteriorly within the fusiform region. The positive association between encoding-related activation and adaptation suggests that over an entire test set, memory performance can be determined by neural events occurring in the peristimulus period. This may reflect stronger engagement of attention at encoding.
腹侧视觉通路中的功能磁共振适应反映了可能有助于内隐和外显记忆的信息处理过程。在采用小于1秒重复滞后的实验中，我们发现注意力增强了视觉处理层级顶端脑区（前梭状回和海马旁回）中重复物体的适应，但在双侧大部分梭状回中，即使注意力最少时它仍会出现。在显示适应的腹侧视觉区域中，海马旁区域和外侧枕叶皮层在受试者中显示出适应幅度与识别记忆之间最强的相关性。虽然存在一些重叠，但显示适应与启动之间相关性的区域在梭状回区域内更靠后。编码相关激活与适应之间的正相关表明，在整个测试集中，记忆表现可由刺激期周围发生的神经事件决定。这可能反映了编码时注意力更强的参与。
