[Prediction of multiple organ failure due to sepsis at the patients with purulo-necrotic diseases of soft tissues].

Microcirculatory disorders at sepsis lead to severe tissue perfusion injury and multiple organ dysfunction. Level of decrease of albumin serum concentration may be used as marker of microcirculatory disorders. One hundred and forty patients with purulo-necrotic diseases of soft tissues were examined. It was demonstrated that intensity of systemic inflammatory reaction (SIR) and old age of patients are the independent risk factors of severe sepsis; multiple organ failure is associated with significant decrease of albumin serum concentration with slight symptoms of SIR. Numeric criteria of risk assessment and 3 risk category of sepsis and multiple organ failure are formulated.