Quartier Pierre, Prieur Anne-Marie
Unité d'immunologie-hématologie et rhumatologie pédiatriques, Centre de référence national labellisé "Arthrites juvéniles , hôpital Necker-Enfants malades, 75743 Paris 15.
Rev Prat. 2007 Jun 15;57(11):1171-8.
Juvenile idiopathic arthritis (JIA), formerly know as juvenile chronic arthritis, is a broad term encompassing several disorders starting before the age of 16. It is characterized by arthritis lasting more than 6 weeks, of unknown etiology, usually persisting for six month initially. Approximately 1 in 5 000 children are affected in France. Of the various distinguishable clinical forms, oligoarticular JIA is the most frequent one. It is characterized by an involvement of up to 4 joints during the first 6 months and is mostly observed in females. The prognosis may be further complicated by the presence of uveitis, associated with an insidious progression. In systemic JIA (also called Still's disease) as well as in some polyarticular forms, with or without rheumatoid factor, inflammation may continue in adulthood. Severe polyarticular involvement or hip involvement may be associated with a poor functional prognosis.
青少年特发性关节炎(JIA),以前称为青少年慢性关节炎,是一个广义术语,涵盖16岁之前发病的多种病症。其特征为关节炎持续超过6周,病因不明,最初通常持续6个月。在法国,每5000名儿童中约有1人受影响。在各种可区分的临床类型中,少关节型JIA最为常见。其特征是在最初6个月内累及多达4个关节,且多见于女性。葡萄膜炎的存在可能会使预后进一步复杂化,葡萄膜炎进展隐匿。在全身型JIA(也称为斯蒂尔病)以及一些多关节型(无论有无类风湿因子)中,炎症在成年期可能会持续。严重的多关节受累或髋关节受累可能与功能预后不良有关。