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儿童脑源性痉挛的手术治疗

Surgical management of spasticity of cerebral origin in children.

作者信息

Sgouros S

机构信息

Department of Neurosurgery, Birmingham Children's Hospital, Birmingham, UK.

出版信息

Acta Neurochir Suppl. 2007;97(Pt 1):193-203. doi: 10.1007/978-3-211-33079-1_27.

Abstract

In children, spasticity is commonly seen in the context of cerebral palsy (CP), but also following head injury, cerebral infarct or other brain insults. CP is a wide term used to describe a constellation of symptoms that characterise the physical impairment of movement due to abnormal brain development. The management of spasticity is tailored according to the clinical picture of the child. Ambulatory mild spastic diplegics tend to reach the maximum of their disability in the first few years of life, and change little after the age of 5-7 years. Such patients who are between 3-5 years and who attempt to mobilise with walking frames are often good candidates for either dorsal rhizotomy or intrathecal baclofen (ITB) administration with the implantation of an indwelling pump. Non-ambulatory mild spastic diplegics and spastic quadriplegics have more profound spasticity, painful spasms, orthopaedic deformities, and difficulties with daily care and posture. ITB has become established as the first line of surgical treatment for these patients. In the last decade, there has been a definite trend away from ablative treatments and towards reversible stimulation and infusion systems. Current pumps have practical limitations but, in the next decade, it is anticipated that technological improvements will render the pumps more patient friendly.

摘要

在儿童中,痉挛常见于脑瘫(CP)的情况下,但也可发生于头部受伤、脑梗死或其他脑部损伤之后。CP是一个宽泛的术语,用于描述因脑发育异常导致运动功能受损的一系列症状。痉挛的治疗是根据患儿的临床表现量身定制的。能行走的轻度痉挛性双侧瘫患儿往往在生命的最初几年达到其最大残疾程度,5 - 7岁以后变化不大。这类3 - 5岁且试图使用助行架活动的患儿通常是进行背根切断术或鞘内注射巴氯芬(ITB)并植入留置泵的良好候选者。不能行走的轻度痉挛性双侧瘫患儿和痉挛性四肢瘫患儿的痉挛更为严重,伴有疼痛性痉挛、骨科畸形以及日常护理和姿势方面的困难。ITB已成为这些患儿外科治疗的一线方法。在过去十年中,出现了一种明确的趋势,即从毁损性治疗转向可逆性刺激和输注系统。目前的泵存在实际局限性,但预计在未来十年,技术改进将使这些泵对患者更加友好。

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