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[侵袭性真菌感染的谱与危险因素]

[Spectrum and risk factors of invasive fungal infection].

作者信息

Osorio Juan José Castón, Román Antonio Rivero, Torre-Cisneros Julián

机构信息

Unidad de Gestión Clínica de Enfermedades Infecciosas, Hospital Universitario Reina Sofía, Córdoba, España.

出版信息

Enferm Infecc Microbiol Clin. 2007 Aug-Sep;25(7):467-76. doi: 10.1157/13108710.

Abstract

In recent years, invasive fungal infection has become a growing problem in immunosuppressed patients. Simultaneously, changes in medical practice, such as the use of anti-Candida prophylaxis with azoles, has led to a shift in the epidemiology of these infections from Candida spp. to Aspergillus and other filamentous molds. Moreover, new risk factors for invasive fungal infection have been identified and the time of onset is different from that seen a decade ago. Recognition of these trends in patients receiving novel immunosuppressive regimens has important implications for the clinical management of fungal infection in this population.

摘要

近年来,侵袭性真菌感染在免疫抑制患者中已成为一个日益严重的问题。与此同时,医疗实践中的变化,如使用唑类进行抗念珠菌预防,已导致这些感染的流行病学从念珠菌属转向曲霉和其他丝状霉菌。此外,已确定了侵袭性真菌感染的新危险因素,且发病时间与十年前不同。认识到接受新型免疫抑制方案的患者中的这些趋势,对于该人群真菌感染的临床管理具有重要意义。

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