Liu Yu-Cheng, Chen Kuen-Bao, Chan Yang-Kee, Hung Chih-Jen, Chang Chia-Sheng, Wong Kar-Lok, Wu Rick Sai-Chuen
Department of Anesthesia, Pain Service and Critical Care Medicine, China Medical University Hospital, Taichung, Taiwan, ROC.
Acta Anaesthesiol Taiwan. 2007 Jun;45(2):121-5.
Syndrome of inappropriate secretion of antidiuretic hormone and diabetes insipidus occurring in very short order in the same patient is rare. We report a 9 month-old male infant suffering form holoprosencephaly developed syndrome of inappropriate secretion of antidiuretic hormone followed by diabetes insipidus within a relative short time postoperatively after his third operation. Inability to suppress as well as to stimulate arginine vasopressin secretion and anesthetic and surgical stresses, were thought to be the possible causes of this event.
抗利尿激素分泌不当综合征和尿崩症在同一患者中短时间内先后出现的情况较为罕见。我们报告了一名9个月大患全前脑畸形的男婴,在其第三次手术后的相对短时间内,先出现了抗利尿激素分泌不当综合征,随后又出现了尿崩症。精氨酸加压素分泌既不能被抑制也不能被刺激以及麻醉和手术应激被认为是这一事件的可能原因。