Bonilla David J, Mains Lindsay, Whitaker Rachel, Crawford Benjamin, Finan Michael, Magnus Manya
Department of Obstetrics and Gynecology, Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA.
J Reprod Med. 2007 Jun;52(6):490-8.
To determine if an enlarged uterus is associated with an increased rate of intraoperative and postoperative complications and prolonged hospital length of stay (LOS) after benign total abdominal hysterectomy (TAH) or total laparoscopic hysterectomy (TLH).
Women who underwent TAH or TLH were stratified, according to uterine weight, into 3 groups: group 1, uterine weight < 200 g; group 2, 201-500 g; and group 3, > 500 g. Indications included uterine leiomyomas, chronic pelvic pain, prolapsed uterus, endometriosis and adenomyosis, dysfunctional uterine bleeding; all had benign final pathology. Statistical analysis compared risks of intraoperative and postoperative morbidity and prolonged hospital stay.
Prolonged hospital stay risk increased for uterine weight > 500 g (p < or = 0.001). There was a significant association between postoperative complications and uterine size (p < or = 0.001). Mean estimated blood loss (EBL) also increased with uterine weight > 500 g (p < or = 0.001). TLH was associated with fewer postoperative complications, shorter LOS and reduced EBL (p < or = 0.001).
Average LOS and risk of blood loss, blood transfusion and other postoperative complications after hysterectomy for benign disease increased with increasing uterine weight. TLH is an excellent alternative for enlarged uteri; it was strongly associated with decreased morbidity, shorter LOS, and reduced EBL and blood transfusion rate in all uterine weight groups when adjusted for other variables.
确定在良性全腹子宫切除术(TAH)或全腹腔镜子宫切除术(TLH)后,子宫增大是否与术中及术后并发症发生率增加以及住院时间延长相关。
接受TAH或TLH的女性根据子宫重量分为3组:第1组,子宫重量<200克;第2组,201 - 500克;第3组,>500克。适应证包括子宫肌瘤、慢性盆腔疼痛、子宫脱垂、子宫内膜异位症和子宫腺肌病、功能失调性子宫出血;所有患者最终病理均为良性。统计分析比较了术中及术后发病风险和住院时间延长情况。
子宫重量>500克时,住院时间延长风险增加(p≤0.001)。术后并发症与子宫大小之间存在显著关联(p≤0.001)。子宫重量>500克时,平均估计失血量(EBL)也增加(p≤0.001)。TLH与较少的术后并发症、较短的住院时间和减少的EBL相关(p≤0.001)。
良性疾病子宫切除术后的平均住院时间以及失血、输血和其他术后并发症的风险随子宫重量增加而增加。TLH是子宫增大患者的极佳替代方案;在调整其他变量后,在所有子宫重量组中,它与发病率降低、住院时间缩短、EBL和输血率降低密切相关。