[健康新生儿的胃电图模式]

Jiang Yu, Wu Jian-Wei, Wu Yun-Sheng

Department of Pediatrics, People's Hospital of Songgang, Shenzhen, Guangdong 518105, China.

Zhongguo Dang Dai Er Ke Za Zhi. 2007 Aug;9(4):364-6.

OBJECTIVE

To investigate the electrogastrogram (EGG) characteristics of healthy neonates.

METHODS

Twenty healthy neonates born at 37-39 weeks of gestation (11 males and 9 females, Apagar's score 9.3 +/- 0.4) were enrolled in this study. EGG recordings were performed for half an hour pre- and postprandially at an interval of a week from birth until age 4 weeks. The EEG variables measured included the percentage of normal gastric rhythm, the percentage of tachygastria and bradygastria, the fed-to-fasting ratio of the EEG dominant power, as well as the EEG dominant frequency and its instability coefficient. The paired sample t test (95% CI) was used to compare the recordings.

RESULTS

Between birth and age 28 days, the percentage of normal gastric rhythm ranged from 38.2 +/- 4.9% to 39.7 +/- 3.5% of recorded time, tachygastria was observed in the range of 23.7 +/- 5.4% to 23.5 +/- 4.3% of recorded time, and bradygastria was shown to be in the range of 38.1 +/- 5.5% to 36.8 +/- 3.9% of recorded time in the 20 neonates before meal. Statistically significant differences were not seen in neonates with different ages as well as during pre- and postprandial periods. The EEG dominant frequency of neonates before meal was 2.38 +/- 0.5, 2.43 +/- 0.2, 2.54 +/- 0.3, 2.57 +/- 0.2 and 2.59 +/- 0.1 cpm at birth and at postnatal age of 7, 14, 21 and 28 days respectively. There were no significant differences in the dominant frequency and the coefficient of instability of the dominant frequency during pre- and postprandial periods. The EEG dominant frequency at postnatal age of 14, 21 and 28 days during pre- and postprandial periods was significantly higher than that at birth and at postnatal age of 7 days (P < 0.05). The coefficient of instability of the dominant frequency at postnatal age of 21 and 28 days was significantly lower than that at birth and at postnatal age of 7 and 14 days (P < 0.05). There were no statistically significant differences in the fed-to-fasting ratio of EGG dominant power in neonates with different ages.

CONCLUSIONS

The pattern of electrical activity in the normal neonatal stomach appears to be different from that demonstrated in adults and children. The percentage of normal gastric rhythm is lower, and tachygastria and bradygastria are more frequently seen. The EEG dominant frequency increases with postnatal age in neonates.

目的

探讨健康新生儿的胃电图（EGG）特征。

方法

选取20例孕37 - 39周出生的健康新生儿（男11例，女9例，阿氏评分9.3±0.4）纳入本研究。从出生至4周龄，每隔一周在餐前和餐后进行半小时的EGG记录。测量的EGG变量包括正常胃节律百分比、过速胃动和过缓胃动百分比、EGG主导功率的进食与禁食比值，以及EGG主导频率及其不稳定系数。采用配对样本t检验（95%置信区间）比较记录结果。

结果

在出生至28日龄期间，20例新生儿餐前正常胃节律百分比在记录时间的38.2±4.9%至39.7±3.5%之间，过速胃动出现在记录时间的23.7±5.4%至23.5±4.3%之间，过缓胃动出现在记录时间的38.1±5.5%至36.8±3.9%之间。不同年龄新生儿以及餐前和餐后期间均未观察到统计学上的显著差异。新生儿餐前的EGG主导频率在出生时以及出生后7、14、21和28日龄分别为2.38±0.5、2.43±0.2、2.54±0.3、2.57±0.2和2.59±0.1次/分钟。餐前和餐后期间主导频率及其不稳定系数均无显著差异。出生后14、21和28日龄餐前和餐后期间的EGG主导频率显著高于出生时和出生后7日龄（P < 0.05）。出生后21和28日龄主导频率的不稳定系数显著低于出生时以及出生后7和14日龄（P < 0.05）。不同年龄新生儿EGG主导功率的进食与禁食比值无统计学显著差异。