Bozgeyik Zulkif, Ozdemir Huseyin, Demirdag Kutbettin, Ozden Mehmet, Sonmezgoz Fitnet, Ozgocmen Salih
Department of Radiology, Faculty of Medicine, Firat University, 23119 Elazig, Turkey.
Eur J Radiol. 2008 Jul;67(1):153-8. doi: 10.1016/j.ejrad.2007.07.002. Epub 2007 Aug 15.
The aim of this retrospective study was to report the clinical features and MR imaging findings of patients with brucellar spondylodiscitis.
Twenty-two patients with spondylodiscitis, recruited among 152 patients with brucellosis referred from the Department of Infectious Diseases. Patients were diagnosed based on positive clinical findings, > or =1/160 titers of brucella agglutination tests and/or positive blood cultures. Magnetic resonance imaging (MRI) was performed to all of the patients with spondylodiscitis. Signal changes and enhancement of vertebral bodies, involvement of paravertebral soft tissues and epidural spaces, nerve root and cord compression and abscess formation were assessed.
All of the patients (n=22; 7 F, 15 M) had > or =1/160 titers of brucella agglutination test and blood culture was positive in 9. A great majority of the patients had involvement at only one vertebrae level (n=21, 95.5%), whereas one patient (4.5%) had multilevel involvement. In MRI, eight patients had soft tissue involvement and three had abscess formation. All cases had vertebral and discal enhancement. Additionally epidural extension was detected in four cases, posterior longitudinal ligament (PLL) elevation in five cases and root compression in two cases.
Brucella is still a public health problem in endemic areas. MRI is a highly sensitive and non-invasive imaging technique which should be first choice of imaging in the early diagnosis of spondylodiscitis.
本回顾性研究旨在报告布鲁氏菌性脊椎椎间盘炎患者的临床特征及磁共振成像(MR)表现。
从传染病科转诊的152例布鲁氏菌病患者中招募了22例脊椎椎间盘炎患者。根据阳性临床发现、布鲁氏菌凝集试验滴度≥1/160和/或血培养阳性进行诊断。对所有脊椎椎间盘炎患者均行磁共振成像(MRI)检查。评估椎体的信号变化及强化情况、椎旁软组织和硬膜外间隙受累情况、神经根及脊髓受压情况以及脓肿形成情况。
所有患者(n = 22;女性7例,男性15例)布鲁氏菌凝集试验滴度均≥1/160,9例血培养阳性。绝大多数患者仅累及一个椎体节段(n = 21,95.5%),而1例患者(4.5%)为多节段受累。MRI检查显示,8例患者有软组织受累,3例有脓肿形成。所有病例均有椎体和椎间盘强化。此外,4例发现硬膜外扩展,5例发现后纵韧带(PLL)抬高,2例发现神经根受压。
在流行地区,布鲁氏菌仍是一个公共卫生问题。MRI是一种高度敏感的非侵入性成像技术,应作为脊椎椎间盘炎早期诊断的首选成像方法。