Liang Dongke, Yang Dazhi, Qi Min
School of Material Engineering, Dalian University of Technology, Dalian 116023, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2007 Jun;24(3):549-53.
Stent implantation can cause thrombus, vessel injury and blood flow disturbance which are considered as the main causes of instent restenosis. In order to investigate the influence of stent implantation on vessel wall and blood flow, we used finite element method (FEM) and computational fluid dynamics (CFD) in this work. The results showed that the implantation of the stent could cause vessel injury and flow stagnation. The instant recoil of the implanted stent is much more than that of the stent itself (12.3% versus 3.1%). In conclusion, FEM and CFD can help illustrate and quantify some biomechanical characteristics for the optimization of stent design.
支架植入可导致血栓形成、血管损伤和血流紊乱,这些被认为是支架内再狭窄的主要原因。为了研究支架植入对血管壁和血流的影响,我们在这项研究中采用了有限元方法(FEM)和计算流体动力学(CFD)。结果表明,支架植入会导致血管损伤和血流停滞。植入支架的即时回缩远大于支架本身的回缩(12.3%对3.1%)。总之,有限元方法和计算流体动力学有助于阐明和量化一些生物力学特性,以优化支架设计。