Esquivel Amanda O, Dawe Elizabeth J, Sala-Mercado Javier A, Hammond Robert L, Bir Cynthia A
Biomedical Engineering, College of Engineering, Wayne State University, Detroit, MI 48201, USA.
Ann Emerg Med. 2007 Nov;50(5):576-83. doi: 10.1016/j.annemergmed.2007.05.003. Epub 2007 Aug 23.
By using an animal model, we determine whether repeated exposures to a conducted electrical weapon could have physiologic consequences.
Exposures to the Stinger S-400 conducted electrical weapon were applied to 10 healthy, anesthetized, Yorkshire-cross, male swine by attaching probes from the cartridge to the sternal notch and anterolateral thorax at a distance of 21.5 cm. The standard pulse generated by the Stinger S-400 during the normal application was applied 20 times during 31 minutes. To evaluate the health effects of the exposures, key physiologic characteristics were evaluated, including arterial pH, PCO2, PO2, blood lactate, cardiac output, ECG, pulse rate, mean arterial pressure, central venous pressure, pulmonary artery pressure and airway pressure, and the cardiac marker troponin I.
There were notable changes in pH, PCO2, blood lactate, cardiac output, and mean arterial pressure after 1 or more sets of exposures, all of which normalized during the next few hours. Troponin I, PO2, pulse rate, mean arterial pressure, central venous pressure, pulmonary artery pressure, and airway pressure did not change markedly during or after the shocks. Three premature ventricular contractions occurred in one animal; all other ECG results were normal.
Repeated exposures to a conducted electrical weapon result in respiratory acidosis, metabolic vasodilation, and an increase in blood lactate level. These effects were transient in this study, with full recovery by 4 hours postexposure. The Stinger S-400 appears to have no serious adverse physiologic effects on healthy, anesthetized swine.
通过使用动物模型,我们确定反复暴露于电击武器是否会产生生理后果。
将Stinger S - 400电击武器的探头连接到10只健康、麻醉的约克夏杂交雄性猪的胸骨切迹和胸前外侧,距离为21.5厘米,对其进行电击。在31分钟内,Stinger S - 400在正常使用时产生的标准脉冲被施加20次。为了评估电击暴露的健康影响,对关键生理特征进行了评估,包括动脉血pH值、二氧化碳分压(PCO2)、氧分压(PO2)、血乳酸、心输出量、心电图、脉搏率、平均动脉压、中心静脉压、肺动脉压和气道压力,以及心脏标志物肌钙蛋白I。
在1组或更多组电击暴露后,pH值、PCO2、血乳酸、心输出量和平均动脉压有显著变化,但在接下来的几个小时内均恢复正常。肌钙蛋白I、PO2、脉搏率、平均动脉压、中心静脉压、肺动脉压和气道压力在电击期间或之后没有明显变化。一只动物出现了三次室性早搏;所有其他心电图结果均正常。
反复暴露于电击武器会导致呼吸性酸中毒、代谢性血管舒张和血乳酸水平升高。在本研究中,这些影响是短暂的,暴露后4小时完全恢复。Stinger S - 400似乎对健康、麻醉的猪没有严重的不良生理影响。