Bashton Matthew, Nobeli Irene, Thornton Janet M
EMBL-European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.
Nucleic Acids Res. 2008 Jan;36(Database issue):D618-22. doi: 10.1093/nar/gkm611. Epub 2007 Aug 24.
PROCOGNATE is a database of protein cognate ligands for the domains in enzyme structures as described by CATH, SCOP and Pfam, and is available as an interactive website or a flat file. This article gives an overview of the database and its generation and presents a new website front end, as well as recent increased coverage in our dataset via inclusion of Pfam domains. We also describe navigation of the website and its features. The current version (1.3) of PROCOGNATE covers 4123, 4536, 5876 structures and 377, 326, 695 superfamilies/families in CATH, SCOP and Pfam, respectively. PROCOGNATE can be accessed at: http://www.ebi.ac.uk/thornton-srv/databases/procognate/
PROCOGNATE是一个关于酶结构中由CATH、SCOP和Pfam描述的结构域的蛋白质同源配体数据库，可通过交互式网站或平面文件获取。本文概述了该数据库及其生成过程，展示了一个新的网站前端，以及通过纳入Pfam结构域，我们的数据集中最近增加的覆盖范围。我们还描述了该网站的导航及其功能。PROCOGNATE的当前版本（1.3）分别涵盖了CATH、SCOP和Pfam中的4123、4536、5876个结构以及377、326、695个超家族/家族。可通过以下网址访问PROCOGNATE：http://www.ebi.ac.uk/thornton-srv/databases/procognate/
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