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一名尼日利亚人鼻腔和鼻窦的恶性神经鞘瘤

Malignant schwannoma of the nasal cavity and paranasal sinuses in a Nigerian.

作者信息

Ogunleye A O A, Ijaduola G T A, Malomo A O, Oluwatosin O M, Shokunbi W A, Akinyemi O A, Oluwasola A O, Akang E E U

机构信息

Department of Otorhinolaryngology, College of Medicine, University of Ibadan and University College Hospital, Ibadan, Nigeria.

出版信息

Afr J Med Med Sci. 2006 Dec;35(4):489-93.

Abstract

An unusual case of malignant schwannoma with involvement of the forehead, external nose, right nasal cavity, paranasal sinus system (bilateral frontal sinus, right ethmoidal sinus), right orbit and anterior cranial fossa is reported in a Nigerian. Malignant schwannomas of the paranasal sinus are extremely rare, as only 20 well-documented cases have been previously published in English literature. No report in black Africans has been found in extant literature. The clinical features of this tumour are presented with detailed management. The patient had a wide surgical resection of the lesion with reconstruction of the resultant fronto-nasal defect using forehead musculofascial flap plus full thickness skin graft and adjuvant radiotherapy with satisfactory outcome. The good result of combined surgery and radiation regimens in this case demonstrates the usefulness of adjuvant radiation therapy in this condition.

摘要

一名尼日利亚人身上报告了一例罕见的恶性神经鞘瘤,该肿瘤累及前额、外鼻、右侧鼻腔、鼻窦系统(双侧额窦、右侧筛窦)、右侧眼眶和前颅窝。鼻窦恶性神经鞘瘤极为罕见,此前英文文献中仅发表过20例有充分记录的病例。现有文献中未发现关于非洲黑人的相关报道。本文介绍了该肿瘤的临床特征及详细治疗过程。患者接受了病变的广泛手术切除,使用额部肌筋膜瓣加全厚皮片修复术后额鼻缺损,并接受了辅助放疗,结果令人满意。该病例中联合手术和放疗方案取得的良好效果证明了辅助放疗在这种情况下的有效性。

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