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合成代谢雄激素类固醇的发展历程。

The history of the development of anabolic-androgenic steroids.

作者信息

Dotson Jennifer L, Brown Robert T

机构信息

Department of Pediatrics, Columbus Children's Hospital, 700 Children's Drive, Columbus, OH 43205, USA.

出版信息

Pediatr Clin North Am. 2007 Aug;54(4):761-9, xi. doi: 10.1016/j.pcl.2007.04.003.

Abstract

The history of anabolic-androgenic steroids (AASs) is an interesting tale that has its roots in ancient "endocrinology." More than 6000 years ago, farmers noted enhanced domestication of animals after castration. The development of AASs, and, later, their artificial synthesis, have remained a hot topic in scientific research and pharmaceuticals. Over the years, AASs have been used as a proposed treatment for a wide variety of ailments, despite deleterious side effects. Unfortunately, they have been, and still are, abused by body builders, athletes, and teens.

摘要

合成代谢雄激素类固醇(AASs)的历史是一个有趣的故事,其根源可追溯到古代的“内分泌学”。六千多年前,农民们注意到阉割后动物的驯化程度提高。AASs的发展以及后来的人工合成,一直是科研和制药领域的热门话题。多年来,尽管存在有害副作用,AASs仍被用作多种疾病的一种治疗方法。不幸的是,它们过去一直被、现在仍然被健美运动员、运动员和青少年滥用。

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