Sehu A, Ergün L, Cakir S, Ergün E, Cantekin Z, Sahin T, Essiz D, Sareyyüpoğlu B, Gürel Y, Yiğit Y
Department of Animal Nutrition and Nutritional Disease, Faculty of Veterinary Medicine, University of Ankara, Ankara,Turkey.
Dtsch Tierarztl Wochenschr. 2007 Jul;114(7):252-9.
The purpose of the present study was to evaluate the toxic effects of aflatoxin (AF) on growth performance and various processing parameters of quails and to determine the preventive efficacy of hydrated sodium calcium aluminosilicate (HSCAS). One hundred and eighty 1-d-old quails of both sexes were randomly divided into 4 experimental groups with 5 replicates and 45 birds following weighing. The experimental design consisted of four dietary treatments: 1) control with 0 mg AF/kg of diet and 0% HSCAS; 2) 0.5% HSCAS; 3) 2.5 mg AF/kg of diet; 4) 2.5 mg AF/kg of diet plus 0.5% HSCAS. The chicks were housed in electrically heated battery cages and exposed to light for 24 h from hatching to 3 weeks of age. Quails consumed the diets and water ad libitum. Body weight (BW) was significantly (p < 0.001) increased by addition of HSCAS to AF diet. The lowest BW gains in groups received AF alone was observed at all periods. The reduction in BW gain caused by 2.5 mg AF/kg of diet was significantly (p < 0.001) diminished by the addition of 0.5% HSCAS to the diet. The addition of HSCAS to the AF diet significantly (p < 0.001) protected against decrease of feed intake at all periods with exception of the first period. None of the treatments altered significantly the feed conversion ratio (FCR). The relative weights of the liver, kidney and spleen were increased in the chickens consuming the AF alone diet. However, light microscopic examination demonstrated the addition of HSCAS to quail feed to partially decrease fat deposition caused by the toxin, and besides, electron microscopic examination of indicated a reorganization in the endoplasmic reticulum and increase in the number of ribosomes and polisomes. Furthermore, the decrease in the antibody titre induced by Newcastle vaccine, due to aflatoxins, was relatively prevented. No significant differences were observed for serum total protein, total cholesterol and glucose levels. The results of indicate that HSCAS is effective in preventing the deleterious effects of AF.
本研究的目的是评估黄曲霉毒素（AF）对鹌鹑生长性能和各种加工参数的毒性作用，并确定水合硅铝酸钙钠（HSCAS）的预防效果。180只1日龄雌雄鹌鹑称重后随机分为4个实验组，每组5个重复，每组45只。实验设计包括四种日粮处理：1）对照组，日粮中AF含量为0 mg/kg，HSCAS含量为0%；2）0.5% HSCAS；3）日粮中AF含量为2.5 mg/kg；4）日粮中AF含量为2.5 mg/kg加0.5% HSCAS。雏鸡饲养在电加热的层叠式笼中，从孵化到3周龄每天光照24小时。鹌鹑自由采食日粮和饮水。在AF日粮中添加HSCAS可显著（p < 0.001）提高体重（BW）。在所有时期，单独饲喂AF的组体重增加最低。日粮中添加0.5% HSCAS可显著（p < 0.001）减轻2.5 mg AF/kg日粮引起的体重增加减少。在AF日粮中添加HSCAS可显著（p < 0.001）防止除第一期外所有时期采食量的下降。所有处理均未显著改变饲料转化率（FCR）。单独饲喂AF日粮的鸡肝脏、肾脏和脾脏的相对重量增加。然而，光学显微镜检查表明，在鹌鹑饲料中添加HSCAS可部分减少毒素引起的脂肪沉积，此外，电子显微镜检查表明内质网发生重组，核糖体和多核糖体数量增加。此外，黄曲霉毒素引起的新城疫疫苗诱导抗体滴度的下降得到了相对预防。血清总蛋白、总胆固醇和葡萄糖水平未观察到显著差异。结果表明，HSCAS可有效预防AF的有害影响。
