Suppr超能文献

[眼部结核病]

[Ocular tuberculosis].

作者信息

De Benedetti Z M Elena, Carranza L Bárbara, Gotuzzo H Eduardo, Rolando C Isaías

机构信息

Instituto de Medicina Tropical Alexander Von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Perú

出版信息

Rev Chilena Infectol. 2007 Aug;24(4):284-95. doi: 10.4067/s0716-10182007000400004. Epub 2007 Aug 20.

Abstract

Tuberculosis (TB) is considered a public health problem in several countries. This disease is classified as either pulmonary or extrapulmonary. Within the extrapulmonary disease, ocular involvement is uncommon but it is important to recognize it because its incidence has been reported up to 1%. Ocular TB cases can be divided in primary and secondary. These manifestations can be caused by an active infection that invades the eye or by an immunologic reaction of delayed hypersensitivity in absence of the infectious agent. The most common clinical presentations are: chronic anterior uveitis, choroiditis and sclerokeratitis. Despite the existence of highly sensitive molecular diagnostic techniques, the diagnosis of ocular tuberculosis continues to be presumptive, based upon clinical presentation, systemic evaluation and response to treatment. For the treatment we use four drugs during a two month period (isoniazid, rifampin, pyrazinamide and ethambutol) and two drugs for four additional months.

摘要

结核病在一些国家被视为公共卫生问题。这种疾病分为肺结核和肺外结核。在肺外结核中,眼部受累并不常见,但认识到这一点很重要,因为据报道其发病率高达1%。眼部结核病例可分为原发性和继发性。这些表现可能由侵入眼睛的活动性感染引起,也可能由在无感染病原体情况下的迟发型超敏反应免疫反应引起。最常见的临床表现为:慢性前葡萄膜炎、脉络膜炎和硬化性角膜炎。尽管存在高度敏感的分子诊断技术,但眼部结核病的诊断仍然是基于临床表现、全身评估和治疗反应的推测性诊断。治疗时,我们在两个月内使用四种药物(异烟肼、利福平、吡嗪酰胺和乙胺丁醇),并在接下来的四个月内使用另外两种药物。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验