Sasaki S, Matsui Y, Gohda T, Sakuma M, Sakai K, Yasuda K, Tanabe T
Department of Cardiovascular Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
Nihon Kyobu Geka Gakkai Zasshi. 1991 Nov;39(11):2006-11.
Since 1980, two different operative strategies were employed during resection to provide distal aortic perfusion by temporary bypass (Group "TB", 39 patients) or partial extracorporeal bypass (Group "PEC", 39 patients) in the operation for the thoracic descending aortic aneurysms or the dissecting aortic aneurysms with DeBakey type III. No significant differences were found in the patient population or the operative procedures between two groups. Mean bypass flow in Group "PEC" was 1850 +/- 70 (ml/min), which is significantly higher than in Group "TB" (1000 +/- 240 ml/min). However, there were no significant differences in the distal aortic pressure between two groups, which was due to administration of vasodilators. Platelet counts in Group "PEC" were significantly lower in the postoperative courses, probably caused by the use of roller pumps or suckers. The incidence of the postoperative renal dysfunction was almost the same in two groups. Cardiac functions during temporary bypass were suppressed by the aortic cross-clamping, therefore, it is necessary to evaluate the cardiac function preoperatively in employing this method. Partial extracorporeal bypass has the disadvantages of the requirement for full heparinization, but it can be indicated to almost all cases, even to the patients with poor cardiac function. It also has the advantage to maintain the distal perfusion in the unexpected intraoperative situations. The method of distal aortic perfusion should be determined by patient-related and disease-related factors.
自1980年以来,在胸降主动脉瘤或DeBakey III型主动脉夹层动脉瘤手术切除过程中,采用了两种不同的手术策略,即通过临时旁路进行远端主动脉灌注(“TB”组,39例患者)或部分体外循环(“PEC”组,39例患者)。两组患者人群或手术操作方面未发现显著差异。“PEC”组的平均旁路流量为1850±70(毫升/分钟),显著高于“TB”组(1000±240毫升/分钟)。然而,两组远端主动脉压力无显著差异,这是由于使用了血管扩张剂。“PEC”组术后血小板计数显著降低,可能是由于使用滚压泵或吸引器所致。两组术后肾功能不全的发生率几乎相同。临时旁路期间的心功能因主动脉阻断而受到抑制,因此,采用该方法时术前评估心功能很有必要。部分体外循环有需要充分肝素化的缺点,但它几乎适用于所有病例,甚至是心功能较差的患者。它还具有在术中意外情况下维持远端灌注的优势。远端主动脉灌注方法应根据患者相关因素和疾病相关因素来确定。