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少动假单胞菌感染:4例报告及文献复习

Infections with Pseudomonas paucimobilis: report of four cases and review.

作者信息

Reina J, Bassa A, Llompart I, Portela D, Borrell N

机构信息

Service of Clinical Microbiology, Hospital Son Dureta, Palma de Mallorca, Spain.

出版信息

Rev Infect Dis. 1991 Nov-Dec;13(6):1072-6. doi: 10.1093/clinids/13.6.1072.

Abstract

Pseudomonas paucimobilis (formerly CDC group IIK, biotype 1) is a strictly aerobic, nonfermenting, oxidase- and catalase-positive, gram-negative bacillus that is widely distributed in water and soil. Its name derives from the difficulty encountered in demonstrating its motility, even in liquid media. This microorganism is responsible for two types of infection in humans: sporadic or community-acquired infections, probably of endogenous or environmental origin (bacteremia, meningitis, urinary tract infection, and wound infection); and outbreaks of nosocomial infection associated with the contamination of sterile fluids employed in hospitals. We present four cases of infection caused by P. paucimobilis (two of bacteremia, one of leg ulcer infection, and one of cervical adenitis). The majority of infections produced by P. paucimobilis have a good prognosis; no deaths related to this entity have been reported in the literature. The published results of susceptibility tests suggest that the aminoglycosides (either alone or in combination with a beta-lactam antibiotic) or the quinolone may be the agents of choice in the treatment of these infections.

摘要

少动假单胞菌(以前称为CDC IIK群,生物型1)是一种严格需氧、不发酵、氧化酶和过氧化氢酶阳性的革兰氏阴性杆菌,广泛分布于水和土壤中。它的名字源于即使在液体培养基中证明其运动性也存在困难。这种微生物可导致人类两种类型的感染:散发性或社区获得性感染,可能源于内源性或环境因素(菌血症、脑膜炎、尿路感染和伤口感染);以及与医院使用的无菌液体污染相关的医院感染暴发。我们报告了4例由少动假单胞菌引起的感染(2例菌血症、1例腿部溃疡感染和1例颈部腺炎)。少动假单胞菌引起的大多数感染预后良好;文献中未报道与该病原体相关的死亡病例。已发表的药敏试验结果表明,氨基糖苷类药物(单独使用或与β-内酰胺类抗生素联合使用)或喹诺酮类药物可能是治疗这些感染的首选药物。

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