莫尔顿植入物治疗慢性闭角型青光眼的长期效果

Long-term results of Molteno implant insertion in cases of chronic angle closure glaucoma.

作者信息

Deokule Sunil P, Molteno Anthony C B, Bevin Tui H, Herbison Peter

机构信息

Eye Department, Dunedin Hospital, Dunedin, New Zealand.

出版信息

Clin Exp Ophthalmol. 2007 Aug;35(6):514-9. doi: 10.1111/j.1442-9071.2007.01530.x.

DOI:10.1111/j.1442-9071.2007.01530.x

PMID:17760632

Abstract

BACKGROUND

This study was undertaken to provide data on the long-term results of cases of chronic angle closure glaucoma with additional risk factors treated by Molteno implants between 1985 and 2004 at Dunedin Hospital, New Zealand.

METHODS

A prospective non-comparative case series followed 21 eyes (17 patients) for a mean of 5.7 years (range 1.3-16.3 years) in terms of intraocular pressure, visual acuity and subsequent procedures.

RESULTS

Insertion of a Molteno implant has controlled the intraocular pressure at 21 mmHg or less in 100% of cases at 5 years after surgery, the probability of control being 0.95 (95% CI 0.91-0.99). The mean number of hypotensive medications reduced from 2.04 (SD 0.92) preoperatively to 1.40, 0.64 and 0.66 at 1, 2 and 5 years, respectively. The mean visual acuity improved from 6/18 preoperatively to 6/12 at 1 year and declined to 6/13.5 at 2 and 5 years.

CONCLUSION

Insertion of Molteno implants was a safe and effective procedure in the management of complex cases of chronic angle closure glaucoma.

摘要

背景

本研究旨在提供1985年至2004年期间，新西兰达尼丁医院采用莫尔顿植入物治疗的伴有其他危险因素的慢性闭角型青光眼病例的长期结果数据。

方法

一项前瞻性非对照病例系列研究，对21只眼（17例患者）进行了平均5.7年（范围1.3 - 16.3年）的眼压、视力及后续手术方面的随访。

结果

莫尔顿植入物植入术后5年，100%的病例眼压控制在21 mmHg或更低，控制概率为0.95（95%可信区间0.91 - 0.99）。降压药物的平均使用数量从术前的2.04（标准差0.92）分别降至术后1年的1.40、2年的0.64和5年的0.66。平均视力从术前的6/18提高到术后1年的6/12，在2年和5年时降至6/13.5。