复合反应元件处的调控串扰
Regulatory crosstalk at composite response elements.
作者信息
Miner J N, Yamamoto K R
机构信息
Department of Biochemistry and Biophysics, University of California, San Francisco 94143-0448.
出版信息
Trends Biochem Sci. 1991 Nov;16(11):423-6. doi: 10.1016/0968-0004(91)90168-u.
PMID:1776172
Abstract
Transcriptional regulatory factors from different families interact with each other when bound to DNA at composite response elements. This level of communication has two striking consequences: ubiquitous factors can effect cell specificity, and closely related factors from a given family can produce very different regulatory patterns.
摘要
来自不同家族的转录调节因子在复合反应元件处与DNA结合时会相互作用。这种交流水平有两个显著后果：普遍存在的因子可以影响细胞特异性，并且来自给定家族的密切相关因子可以产生非常不同的调节模式。
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