Glintborg Bente, Poulsen Henrik E, Dalhoff Kim P
Department of Clinical Pharmacology, Rigshospitalet, Copenhagen, Denmark.
Br J Clin Pharmacol. 2008 Feb;65(2):265-9. doi: 10.1111/j.1365-2125.2007.03017.x. Epub 2007 Aug 31.
Structured medication interviews improve the medication history upon hospitalization. Pharmacy records are valid lists of the prescribed medications available to individual patients. In Denmark, treating doctors now have access to their patients' pharmacy records through a real-time online electronic database What this study adds: Omission errors are frequent among hospitalized patients despite structured drug interviews and home visits. Pharmacy records may be used to minimize patients' recall bias and improve the medication lists.
Structured medication interviews improve the medication history in hospitalized patients. In Denmark, a nationwide electronic version of individual pharmacy records (PR) has recently been introduced. Use of these records could improve the medication lists in hospitalized patients.
We prospectively included 500 patients admitted to an acute medical department. In individual patients, the PR was compared with (i) the medication list written in the patient chart and (ii) drug information provided by the patient during a structured drug interview upon admission and during a home visit after discharge.
Median patient age was 72 years. Upon admission, patients reported using 1958 prescription-only medications (POM) (median four drugs per patient, range 0-14), of which 114 (6%) were not registered in PR. In PR, 1153 POM (median one per patient, range 0-11) were registered during the month preceding admission. The patients did not report 309 (27%) of these upon admission. Home visits were performed in a subgroup of 115 patients. During home visits, 18% of POM registered in PR during the preceding month were not reported. Drug type was predictive of reporting irrespective of patient sex or age. Cardiovascular drugs were reported most and dermatological were reported less frequently. Underreporting might be due to recall bias, non-adherence or discontinuation of drugs.
Omission errors are frequent despite structured medication interviews. Pharmacy records or medication lists from all treating doctors must be included in medication reviews in order to reduce recall bias.
结构化药物访谈可改善住院时的用药史。药房记录是可供个体患者使用的有效处方药清单。在丹麦,主治医生现在可通过实时在线电子数据库访问其患者的药房记录。本研究的新增内容:尽管进行了结构化药物访谈和家访,但住院患者中遗漏错误仍很常见。药房记录可用于尽量减少患者的回忆偏倚并完善用药清单。
结构化药物访谈可改善住院患者的用药史。在丹麦,最近引入了全国性的个体药房记录(PR)电子版。使用这些记录可完善住院患者的用药清单。
我们前瞻性纳入了500名入住急性内科的患者。对于个体患者,将PR与(i)患者病历中书写的用药清单以及(ii)患者在入院时的结构化药物访谈期间和出院后的家访期间提供的药物信息进行比较。
患者年龄中位数为72岁。入院时,患者报告使用了1958种仅凭处方使用的药物(POM)(每位患者中位数为4种药物,范围为0 - 14种),其中114种(6%)未在PR中登记。在PR中,入院前一个月登记了1153种POM(每位患者中位数为1种,范围为0 - 11种)。患者入院时未报告其中的309种(27%)。对115名患者的亚组进行了家访。在家访期间,前一个月在PR中登记的POM中有18%未被报告。药物类型可预测报告情况,与患者性别或年龄无关。心血管药物报告最多,皮肤科药物报告较少。漏报可能是由于回忆偏倚、不依从或停药。
尽管进行了结构化药物访谈,但遗漏错误仍很常见。为减少回忆偏倚,用药评估中必须纳入所有主治医生的药房记录或用药清单。