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伴有致命性出血的脑室内脑膜瘤:临床及尸检结果

Intraventricular meningioma with fatal haemorrhage: clinical and autopsy findings.

作者信息

Romeike Bernd F M, Joellenbeck Boris, Skalej Martin, Scherlach Cordula, Kirches Elmar, Mawrin Christian

机构信息

Abteilung für Neuropathologie, Friedrich-Schiller-Universität, D-07747 Jena, Germany.

出版信息

Clin Neurol Neurosurg. 2007 Dec;109(10):884-7. doi: 10.1016/j.clineuro.2007.07.016. Epub 2007 Aug 30.

Abstract

Only a few cases of intraventricular meningioma have been reported and the association with intracranial haemorrhage is even rarer. More than ever, autopsy findings are scarce. Here, we report a case of primary intraventricular meningioma with intraventricular haemorrhage in a 57-year-old woman. A CT scan of the head initially suggested a malignant brain tumour as the lesion was quite inhomogeneous with hyper- and hypodense sections accompanied by fresh haemorrhage. At autopsy, the tumour was histologically diagnosed as a fibroblastic meningioma WHO-Grade I. The source of haemorrhage was most likely the tumour itself as it contained focally rather large angiomatous and additionally small cavernous vessels and acute haemorrhage in various sections. The assumptive adherence of the tumour to the choroid plexus was probably disrupted by the haematoma.

摘要

仅报道过少数几例脑室内脑膜瘤病例,而其与颅内出血相关的情况更为罕见。尸检结果比以往任何时候都更为稀少。在此,我们报告一例57岁女性原发性脑室内脑膜瘤伴脑室内出血的病例。头部CT扫描最初提示为恶性脑肿瘤,因为病变相当不均匀,有高密度和低密度区域,并伴有新鲜出血。尸检时,肿瘤经组织学诊断为世界卫生组织I级纤维母细胞型脑膜瘤。出血来源很可能是肿瘤本身,因为肿瘤局部含有相当大的血管瘤样血管以及小的海绵状血管,且不同区域有急性出血。肿瘤与脉络丛的假定粘连可能因血肿而中断。

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