Lydtin H
Klin Wochenschr. 1977 May 1;55(9):415-22. doi: 10.1007/BF01488578.
Unwanted effects of beta-receptor blocking agents can be divided into three categories: 1. Those arising specifically from the pharmacologic, i.e., beta-blocking action. 2. Side effects not directly (or not with certainty) related to beta-blockade. 3. Adverse and potentially specific reactions to individual beta-blocking agents. Category 1 covers the majority of adverse effects (heart failure, severe bradycardia and hypotension, arterial insufficiency, increased airways resistance, gastrointestinal symptoms, hypoglycemia). These can largely be avoided by proper selection and preparation of patients. Category 2 covers cutaneous reactions (rashes, alopecia, pruritus), purpura (thrombocytopenic and nonthrombocytopenic) etc. as well as side effects attributable to the central nervous system (antianxiety effects, nightmares etc.). In the third category the "oculo-cutaneous syndrome" associated with practolol is discussed.
β受体阻滞剂的不良反应可分为三类：1. specifically源于药理学作用，即β阻断作用的不良反应。2. 与β阻断无直接（或不确定）关联的副作用。3. 对个别β受体阻滞剂的不良及潜在特异性反应。第一类涵盖了大多数不良反应（心力衰竭、严重心动过缓和低血压、动脉供血不足、气道阻力增加、胃肠道症状、低血糖）。通过对患者进行适当的选择和准备，这些不良反应在很大程度上是可以避免的。第二类包括皮肤反应（皮疹、脱发、瘙痒）、紫癜（血小板减少性和非血小板减少性）等以及归因于中枢神经系统的副作用（抗焦虑作用、噩梦等）。在第三类中，讨论了与心得宁相关的“眼皮肤综合征”。
