Lammie Patrick, Milner Trevor, Houston Robin
Division of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Bull World Health Organ. 2007 Jul;85(7):545-9. doi: 10.2471/blt.06.034108.
Fortifying salt with diethylcarbamazine (DEC) is a safe, low-cost and effective strategy to eliminate transmission of lymphatic filariasis. DEC-fortified salt has been used successfully in pilot projects in several countries and has been used operationally by China to eliminate lymphatic filariasis. The successful use of iodized salt to eliminate iodine-deficiency disorders is encouraging; similarly, fortified salt could be used as a vehicle to eliminate lymphatic filariasis. Despite the potential programmatic advantages of fortifying salt with DEC instead of undertaking mass administration of tablets, DEC-fortified salt remains an underutilized intervention. We discuss the reasons for this and suggest settings in which the use of DEC-fortified salt should be considered.
用乙胺嗪(DEC)强化食盐是消除淋巴丝虫病传播的一种安全、低成本且有效的策略。强化DEC的食盐已在多个国家的试点项目中成功使用,中国也已将其用于消除淋巴丝虫病的实际行动中。成功使用碘盐消除碘缺乏症令人鼓舞;同样,强化食盐也可作为消除淋巴丝虫病的一种手段。尽管用DEC强化食盐而非进行大规模片剂给药具有潜在的项目优势,但强化DEC的食盐仍是一种未得到充分利用的干预措施。我们讨论了其中的原因,并提出了应考虑使用强化DEC食盐的情况。