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[胃癌根治术后乳糜漏的处理]

[Management of chylous leakage after radical operation of gastric cancer].

作者信息

DU Jian-jun, Li Ji-peng, Ding Zhen-ruo, Zheng Jian-yong, Ji Gang, Gao Zhi-qing, Wang Wei-zhong, Dou Ke-feng

机构信息

Department of General Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2007 May 29;87(20):1414-6.

Abstract

OBJECTIVE

To investigate the management of chylous leakage after radical operation of gastric carcinoma.

METHODS

161 patients with gastric carcinoma underwent D2-D4 dissection. A double catheterization cannula was employed in each patient around the abdominal aorta above the celiac trunk and crus of diaphragm. Postoperatively, the chylous fluid from the drainage tube was observed, smeared and cultured; infection of chylous fluid was treated. The development of chylous leakage was observed and the optimal time to remove the drainage tube was determined.

RESULTS

Chylous leakage occurred in 19 patients. The volume of chylous leakage was less than 250 ml/24 h in 8 patients, 250 - 500 ml/24 h in 7, and 500 - 1500 ml/24 h in 4. Candida albicans was founded in the fluid of chylous leakage in 8 patients, and bacterial infection was found simultaneously in 5 of them. The patients with chylous leakage were healed within 10 - 90 postoperative days. The drainage tube was removed when there was no fluid in the tube and no hydrops in peritoneal cavity by B ultrasound, and the patient were in good condition without signs and symptoms of infections.

CONCLUSION

Chylous leakage after D2 - D4 dissection for gastric carcinoma can be cured by immediate diagnosis, thorough drainage, and anti-infectious treatment with regional and continuative washout when the chylous fluid is infected by Candida or bacteria.

摘要

目的

探讨胃癌根治术后乳糜漏的处理方法。

方法

161例胃癌患者行D2 - D4根治性切除术。于每例患者腹腔干上方及膈肌脚周围的腹主动脉旁置入双腔引流管。术后观察引流管引出的乳糜液,进行涂片及培养,对乳糜液感染进行治疗。观察乳糜漏的发生情况,确定拔除引流管的最佳时机。

结果

19例患者发生乳糜漏。乳糜漏量<250 ml/24 h者8例,250~500 ml/24 h者7例,500~1500 ml/24 h者4例。8例乳糜漏液中检出白色念珠菌,其中5例同时合并细菌感染。乳糜漏患者术后10~90天治愈。当引流管无液体引出,B超检查腹腔无积液,患者一般情况良好且无感染体征及症状时拔除引流管。

结论

胃癌D2 - D4根治术后发生乳糜漏,若乳糜液被念珠菌或细菌感染,通过及时诊断、充分引流及局部持续冲洗抗感染治疗可治愈。

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