Hu Wen-Sheng, He Jing, Shen Yuan-Ming, Cai Shu-Ping, Lu Hong
Women's Hospital Zhejiang Universty Medical College, Hangzhou 310006, China.
Zhonghua Yi Xue Za Zhi. 2007 Jun 5;87(21):1491-2.
To explore the diagnosis, clinical course and prognosis of fetal multicystic kidney dysplasia (MCDK).
24 858 pregnant women detected by prenatal ultrasound, here were 41 cases with fetal multicystic kidney dysplasia, these fetuses were diagnosed at average 29.8 weeks of gestation, Carried on an observation to fetuses with multicystic kidney dysplasia and postnatal follow-up study.
T17 cases were induced abortion. Of 13 infants, 1 case involute, 3 cases decrease, 9 cases no change.
Prenatal ultrasonography can actual diagnosis for fetal multicystic kidney dysplasia, the key of management of multicystic kidney dysplasia is assessment of fetal prognosis, the natural history of unilateral MCDK is usually benign, the affected kidneys tend to show involution after birth. But bilateral MCDK often associated with impairement of renal function, abnormal chromosome or other anomalies, which indicates a poor prognosis.
探讨胎儿多囊性肾发育不良(MCDK)的诊断、临床经过及预后。
对24858例孕妇进行产前超声检查,其中41例胎儿患有多囊性肾发育不良,这些胎儿平均在妊娠29.8周时被诊断出来,对多囊性肾发育不良胎儿进行观察及产后随访研究。
17例引产。13例婴儿中,1例肾囊肿消退,3例减少,9例无变化。
产前超声可准确诊断胎儿多囊性肾发育不良,多囊性肾发育不良处理的关键是评估胎儿预后,单侧MCDK的自然病程通常是良性的,患肾在出生后往往会逐渐消退。但双侧MCDK常伴有肾功能损害、染色体异常或其他畸形,提示预后不良。