Akyildiz Elif Ulker, Celik Safa, Ersoy Gökhan
Adalet Bakanliği, Adli Tip Kurumu, Istanbul, Turkey.
Anadolu Kardiyol Derg. 2007 Sep;7(3):253-6.
Characteristics of legal autopsy cases with cardiac rupture following myocardial infarction are investigated in this retrospective observational study and the results are compared with a control group consisting of acute myocardial infarction cases without rupture.
Legal autopsy reports of 50 cases with heart tamponade resulting from heart muscle rupture following myocardial infarction, autopsied at the Morgue Department of the Council of Forensic Medicine between the years 1998-2005 were retrospectively reviewed. Findings were compared to control group consisting of 30 myocardial infarction cases without rupture.
The rupture was located in the left ventricle in 48 of 50 cases. At microscopic examination, infarction date was consistent with first three days, 4-7 days and 1-2 weeks for 30, 12 and 8 cases, respectively. The average volume of fluid leading to tamponade was 467 ml in males and 352.3 ml in females. There were no statistical differences between rupture and control groups for existence of hypertrophy and scar tissue in myocardium and advanced atheromatous lesions in coronaries (p>0.05). Considering the manner of death of the cases died due to heart wall rupture and tamponade formation, 28 of the cases were found dead at home, 6 died suddenly by falling to the ground at home or on the street, and 5 were delivered dead to the hospital.
The rupture was located in the left ventricle in almost all cases. Ruptures in the left ventricle were found most frequently in the anterior wall. There was no relationship between development of rupture and existence of hypertrophy and scar tissue in myocardium, and advanced atheromatous lesions in coronaries.
在这项回顾性观察研究中,对心肌梗死后心脏破裂的法定尸检病例特征进行调查,并将结果与由无破裂的急性心肌梗死病例组成的对照组进行比较。
回顾性审查了1998年至2005年间在法医委员会停尸房进行尸检的50例因心肌梗死后心肌破裂导致心脏压塞的法定尸检报告。将结果与由30例无破裂的心肌梗死病例组成的对照组进行比较。
50例中有48例破裂位于左心室。在显微镜检查中,梗死日期分别与30例、12例和8例的头三天、4至7天和1至2周一致。导致压塞的液体平均量男性为467毫升,女性为352.3毫升。在心肌肥大和瘢痕组织的存在以及冠状动脉严重动脉粥样硬化病变方面,破裂组和对照组之间无统计学差异(p>0.05)。考虑到因心脏壁破裂和压塞形成而死亡的病例的死亡方式,发现28例在家中死亡,6例在家中或街上突然倒地死亡,5例被送到医院时已死亡。
几乎所有病例的破裂都位于左心室。左心室破裂最常见于前壁。破裂的发生与心肌肥大和瘢痕组织的存在以及冠状动脉严重动脉粥样硬化病变之间没有关系。