Strub William M, Brown Thomas A, Ying Jun, Hoffmann Mary, Ernst Robert J, Bulas Robert V
Department of Radiology, University of Cincinnati, Cincinnati, Ohio 45267, USA.
J Vasc Interv Radiol. 2007 Sep;18(9):1151-5. doi: 10.1016/j.jvir.2007.06.011.
To assess the efficacy of translaminar cervical epidural steroid injection (ESI) in the management of localized or radicular neck pain and assess categoric factors that can help predict clinical outcome.
In all patients studied, treatment of neck pain with oral pain medications or physical therapy had failed. A total of 280 translaminar cervical ESIs were performed in 161 patients with an average age of 58 years (range, 26-82 y). The average duration of symptoms until the time the procedure was performed was 18.2 months (range, 0.25-240 months). All patients were assessed by telephone approximately 10 days after the procedure to determine efficacy.
Of the 280 total injections, 233 (83%) resulted in pain relief. Patients were more likely to experience pain relief if they presented with multilevel degenerative changes (odds ratio [OR] = 4.13, P = .0055), had radicular symptoms in the hand and/or finger (OR = 2.72, P = .0011), or underwent injection at the C7-T1 level (OR = 2.44, P = .0034). Patients who required narcotics for their symptoms before the procedure showed lower odds of pain relief (OR = 0.80, P = .4367). There were no major complications and the overall minor complication rate was 5.18%.
Translaminar cervical ESI is a safe procedure. Although repeat injections may be necessary in some patients, excellent short-term clinical results can be achieved.
评估经椎板颈椎硬膜外类固醇注射(ESI)治疗局限性或根性颈部疼痛的疗效,并评估有助于预测临床结果的分类因素。
在所有研究患者中,口服止痛药物或物理治疗对颈部疼痛的治疗均失败。对161例平均年龄58岁(范围26 - 82岁)的患者共进行了280次经椎板颈椎ESI。从症状出现到进行该操作的平均持续时间为18.2个月(范围0.25 - 240个月)。所有患者在操作后约10天通过电话进行评估以确定疗效。
在总共280次注射中,233次(83%)使疼痛缓解。如果患者出现多节段退变改变(优势比[OR]=4.13,P = 0.0055)、手部和/或手指有根性症状(OR = 2.72,P = 0.0011)或在C7 - T1水平进行注射(OR = 2.44,P = 0.0034),则更有可能疼痛缓解。在操作前因症状需要使用麻醉剂治疗的患者疼痛缓解的几率较低(OR = 0.80,P = 0.4367)。未出现重大并发症,总体轻微并发症发生率为5.18%。
经椎板颈椎ESI是一种安全的操作。尽管部分患者可能需要重复注射,但可取得优异 的短期临床效果。